荷兰早发性结直肠癌发病率上升：值得关注吗？］

Q4 Medicine

Nederlands tijdschrift voor geneeskunde Pub Date : 2025-04-24

Marloes A G Elferink, Laskarina J K Galanos, Femke P C Sijtsma, Maarten J Bijlsma, Tineke E Buffart, Ignace H J T de Hingh, Monique E van Leerdam, Felice N van Erning

{"title":"荷兰早发性结直肠癌发病率上升：值得关注吗？］","authors":"Marloes A G Elferink, Laskarina J K Galanos, Femke P C Sijtsma, Maarten J Bijlsma, Tineke E Buffart, Ignace H J T de Hingh, Monique E van Leerdam, Felice N van Erning","doi":"","DOIUrl":null,"url":null,"abstract":"Objective: To describe trends in incidence of early-onset colorectal cancer in the Netherlands.Design: Observational research.Method: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035.Results: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035.Conclusion: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.","PeriodicalId":18903,"journal":{"name":"Nederlands tijdschrift voor geneeskunde","volume":"169 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Rise in incidence of early-onset colorectal cancer in the Netherlands: cause for concern?]\",\"authors\":\"Marloes A G Elferink, Laskarina J K Galanos, Femke P C Sijtsma, Maarten J Bijlsma, Tineke E Buffart, Ignace H J T de Hingh, Monique E van Leerdam, Felice N van Erning\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To describe trends in incidence of early-onset colorectal cancer in the Netherlands.Design: Observational research.Method: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035.Results: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035.Conclusion: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.\",\"PeriodicalId\":18903,\"journal\":{\"name\":\"Nederlands tijdschrift voor geneeskunde\",\"volume\":\"169 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nederlands tijdschrift voor geneeskunde\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nederlands tijdschrift voor geneeskunde","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

目的：描述荷兰早发性结直肠癌的发病率趋势。设计：观察性研究。方法：我们从荷兰癌症登记处（NCR）选择年龄在15至49岁之间，1989-2023年间诊断的结直肠癌患者。我们使用Joinpoint回归分析计算发病率并确定趋势变化。并对2035年我国早发性结直肠癌患者数量进行了预测。结果：早发结直肠癌新发病例有所增加；由1998年的每10万人6.3人上升至2023年的每10万人9.3人（年百分比变化1.41%(95%可信区间1.18-1.71)）。预计未来这一发病率将进一步增加，到2035年将达到629至871例。结论：在荷兰，早发性结直肠癌的发病率呈上升趋势，这一趋势将持续10年。需要进一步的研究来确定这种增加的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Rise in incidence of early-onset colorectal cancer in the Netherlands: cause for concern?]

Objective: To describe trends in incidence of early-onset colorectal cancer in the Netherlands.

Design: Observational research.

Method: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035.

Results: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035.

Conclusion: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nederlands tijdschrift voor geneeskunde Medicine-Medicine (all)

CiteScore

0.30

自引率

0.00%

发文量

302

期刊介绍： Het NTVG staat bekend als hét wetenschappelijke algemene medische tijdschrift. De lange historie en de degelijkheid maken het tijdschrift tot een bolwerk van medische wetenschap in druk. Ook door de goede leesbaarheid draagt het tijdschrift bij aan de voortdurende dialoog over de geneeskunde.