甲磺酸伊马替尼治疗艾滋病毒感染者皮质类固醇难治性特发性嗜酸性粒细胞增多综合征的完全血流变反应：1例报告。

IF 1.4 4区医学 Q4 IMMUNOLOGY

International Journal of STD & AIDS Pub Date : 2025-05-07 DOI:10.1177/09564624251338593

Anna Mira Lubis, Evy Yunihastuti, Agnes Stephanie Harahap, Gabriella Anindyah, Amirah Yasmin, Matdoan Rifkiah Aisyah

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引用次数: 0

摘要

我们报告一例38岁的HIV感染者（PLHIV）被诊断为难治性特发性嗜酸性粒细胞增多综合征（HES）。他最初的症状是瘙痒性皮疹、干咳和腹泻。患者对皮质类固醇作为一线治疗无反应。随后给予甲磺酸伊马替尼100 mg /天的治疗，结果是良好和持续的血液学和临床反应，可能也有分子反应。

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Complete hematological response with imatinib mesylate in a corticosteroid refractory idiopathic hypereosinophilic syndrome in person living with HIV: A case report.

We present a case of a 38-year-old person living with HIV (PLHIV) diagnosed with refractory idiopathic hypereosinophilic syndrome (HES). His initial symptoms were pruritic skin rash, dry cough, and diarrhea. The patient was unresponsive to corticosteroid as a first-line therapy. Subsequent treatment with Imatinib mesylate 100 mg per day resulted in excellent and sustained hematological and clinical response, with a likely molecular response as well.

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来源期刊

International Journal of STD & AIDS 医学-传染病学

CiteScore

2.60

自引率

7.10%

发文量

144

审稿时长

3-6 weeks

期刊介绍： The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).