Dan Zhou, Ran Xu, Jiawei Zhou, Yushan Liu, Shi Zeng
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Changes of Aortic Elastic Properties in Normal Fetuses During the Second Half of Pregnancy.
Objective: The purpose of the study was to observe the elastic properties of the aorta in normal fetuses by M-mode echocardiography.
Methods: This was a prospective cross-sectional study performed in 402 normal fetuses during 20-37 weeks of gestation. The elastic properties of the ascending aorta, thoracic aorta, and abdominal aorta were assessed by diameter strain (DS) which was determined by M-mode echocardiography. DS was defined as 100 × (Dmax - Dmin)/Dmin. Correlations between DS and gestational age and combined cardiac output were assessed by linear regression analysis.
Results: We successfully acquired 377 (93.8%) normal fetal measurements. DS of the ascending aorta, thoracic aorta, and abdominal aorta declined as the gestational age proceeded (b = -0.683, -0.358 and -0.263, p < 0.001), while it increased with combined cardiac output (b = 0.041, 0.03, and 0.017, p < 0.001). DS in the ascending aorta and thoracic aorta were higher than those in the abdominal aorta (p < 0.001), while there was no significant difference between the ascending aorta and thoracic aorta. The reproducibility for DS measurements by M-mode echocardiography was good.
Conclusions: Our results demonstrated a decline in DS with gestational age and variable aortic strain from the proximal to distal segments in the normal fetuses. Intrauterine changes in arterial elastic properties might reflect the maturation of fetal circulation.
期刊介绍：
The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography.
The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents.
JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.
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