Joey F H Reijmer, Thomas J A van Schaik, Mechteld A R Vermeulen, William J M van der Stappen, Steven Strang
{"title":"[双膦酸盐使用导致双侧股骨骨折]。","authors":"Joey F H Reijmer, Thomas J A van Schaik, Mechteld A R Vermeulen, William J M van der Stappen, Steven Strang","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The risk of an atypical femoral fracture increases with the use of bisphosphonates for longer than 5 years. The typical presentation of an atypical femoral fracture consists of a transverse subtrochanteric femoral fracture originating from the lateral cortex with a medial spike, occurring after minimal or no trauma. For patients presenting with a spontaneous femoral fracture who are using bisphosphonates, it is recommended to discontinue bisphosphonate use and to determine the future fracture risk. Imaging of the contralateral femur should always be performed in patients with an AFF. If radiological abnormalities are present, preventive surgical fixation of the contralateral side should be considered. During the first two years following an atypical femoral fracture, regular monitoring with radiographs of both femurs is advised to assess healing and detect potential new fractures.</p>","PeriodicalId":18903,"journal":{"name":"Nederlands tijdschrift voor geneeskunde","volume":"169 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Bilateral femoral fractures due to bisphosphonate use].\",\"authors\":\"Joey F H Reijmer, Thomas J A van Schaik, Mechteld A R Vermeulen, William J M van der Stappen, Steven Strang\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The risk of an atypical femoral fracture increases with the use of bisphosphonates for longer than 5 years. The typical presentation of an atypical femoral fracture consists of a transverse subtrochanteric femoral fracture originating from the lateral cortex with a medial spike, occurring after minimal or no trauma. For patients presenting with a spontaneous femoral fracture who are using bisphosphonates, it is recommended to discontinue bisphosphonate use and to determine the future fracture risk. Imaging of the contralateral femur should always be performed in patients with an AFF. If radiological abnormalities are present, preventive surgical fixation of the contralateral side should be considered. During the first two years following an atypical femoral fracture, regular monitoring with radiographs of both femurs is advised to assess healing and detect potential new fractures.</p>\",\"PeriodicalId\":18903,\"journal\":{\"name\":\"Nederlands tijdschrift voor geneeskunde\",\"volume\":\"169 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nederlands tijdschrift voor geneeskunde\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nederlands tijdschrift voor geneeskunde","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Bilateral femoral fractures due to bisphosphonate use].
The risk of an atypical femoral fracture increases with the use of bisphosphonates for longer than 5 years. The typical presentation of an atypical femoral fracture consists of a transverse subtrochanteric femoral fracture originating from the lateral cortex with a medial spike, occurring after minimal or no trauma. For patients presenting with a spontaneous femoral fracture who are using bisphosphonates, it is recommended to discontinue bisphosphonate use and to determine the future fracture risk. Imaging of the contralateral femur should always be performed in patients with an AFF. If radiological abnormalities are present, preventive surgical fixation of the contralateral side should be considered. During the first two years following an atypical femoral fracture, regular monitoring with radiographs of both femurs is advised to assess healing and detect potential new fractures.
期刊介绍:
Het NTVG staat bekend als hét wetenschappelijke algemene medische tijdschrift. De lange historie en de degelijkheid maken het tijdschrift tot een bolwerk van medische wetenschap in druk. Ook door de goede leesbaarheid draagt het tijdschrift bij aan de voortdurende dialoog over de geneeskunde.