长冠状病毒症状和HRQoL的五个维度：沙特阿拉伯COVID-19感染康复患者的回顾性区域研究

IF 2.1 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

International Journal of General Medicine Pub Date : 2025-05-05 eCollection Date: 2025-01-01 DOI:10.2147/IJGM.S518258

Mokhtar Abdo Almoliky, Bandar Alsaif, Khalil A Saleh, Sameer A Alkubati, Sehar-Un-Nisa Hassan, Fahad D Algahtani, Badr Khalaf Mubarak Aldhmadi, Hamza Mohammad Assaggaf, Mohamed Ali Alzain

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引用次数: 0

摘要

背景/目的：10-20%的冠状病毒感染者有长期的COVID症状，因此，目前的研究是沙特阿拉伯第一个确定COVID-19幸存者长期健康抱怨与健康相关生活质量（HRQoL）之间关系的区域评估。方法：研究人群包括从COVID-19大流行开始到2022年9月在沙特阿拉伯哈伊勒地区登记的COVID-19感染病例。采用回顾性研究设计，295名参与者完成了一份自我报告问卷，以评估长期COVID症状和阿拉伯版本的欧洲5维生活质量（EQ-5D）。采用多元线性回归方法，选择（p值< 0.05）评价长冠状病毒症状对患者HRQoL的预测作用。结果：参与者的平均年龄（SD）为38岁，67.1%为男性，58.6%为已婚。在长时间的COVID-19症状中，平均值最高的是疲劳(M=2.3；95% CI 2.1-2.4)，其次是头痛(M=2.1；95% CI 2.0-2.3)和持续咳嗽(M=1.9；95% ci 1.8-2.1)。研究结果显示，HRQoL在疼痛/不适领域存在问题，该领域的最高平均分(M=4.24；95% CI 4.14-4.33)，其次是焦虑/抑郁（M=4.17: 95% CI 4.08-4.27）。结论：该研究对沙特阿拉伯的卫生部门转型计划具有重要意义，通过解决特定的长期covid症状（如疲劳、持续咳嗽、呼吸困难和性功能障碍）的负面影响，并改善疼痛/不适和焦虑/抑郁领域的HRQoL，可以实现以人为中心的护理和患者满意度的目标。

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Long COVID Symptoms and Five Dimensions of HRQoL: A Retrospective Regional Study of Patients Recovered from COVID-19 Infection in Saudi Arabia.

Background/aim: 10-20% of people infected with the coronavirus infection have long COVID symptoms, therefore, current research is the first regional assessment in Saudi Arabia to determine the relationship between long-term health complaints of COVID-19 survivors and health-related quality of life (HRQoL).

Methods: The study population comprised COVID-19 infection cases registered in the Ha'il region of Saudi Arabia from the beginning of the COVID-19 pandemic until September 2022. A retrospective research design was employed, and 295 participants completed a self-report questionnaire to assess long COVID symptoms and the Arabic version of the European 5-Dimensional Quality of Life (EQ-5D). Multiple linear regression was used to evaluate the predictive role of long COVID symptoms on the HRQoL of patients by choosing (p-value < 0.05).

Results: The mean (SD) age of the participants was 38 years, (67.1%) were male and (58.6%) were married. On the long COVID-19 symptoms, the highest mean values were fatigue (M=2.3; 95% CI 2.1-2.4) followed by headache (M=2.1; 95% CI 2.0-2.3) and persistent cough (M=1.9; 95% CI 1.8-2.1). Findings show that HRQoL was problematic in domains of pain/discomfort as depicted by a highest mean score on this domain (M=4.24; 95% CI 4.14-4.33) followed by anxiety/depression (M=4.17: 95% CI 4.08-4.27). Multiple regression analysis showed that marital status (p=0.05), irregular exercise (p<0.01), duration of hospitalization (p<0.01), and oxygen therapy (p<0.05) were the independent background factors affecting HRQoL post-COVID-19. Among the long-COVID-19 symptoms, fatigue (p=0.05), persistent cough (p=0.001), dyspnea (p=0.02), and sexual dysfunction (p<0.001) were the independent factors that impacted the HRQoL after controlling for background variables.

Conclusion: The study has significant implications for Saudi Arabia's Health Sector Transformation Program that could achieve its goals of human centric care and patient satisfaction though addressing the negative impacts of specific long-COVID symptoms such as fatigue, persistent cough, dyspnea and sexual dysfunction and improving the HRQoL in domains of pain/discomfort and anxiety/depression.

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来源期刊

International Journal of General Medicine Medicine-General Medicine

自引率

0.00%

发文量

1113

审稿时长

16 weeks

期刊介绍： The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal. As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.