{"title":"[A-PRF与CGF对下颌阻生第三磨牙拔牙后恢复及相邻第二磨牙牙槽嵴的影响比较]。","authors":"Li-Li Pu, Chun-Hui Chen, Xi Tong","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare the recovery effect of advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) in the treatment of mandibular impacted third molar(M3) extraction, and the effect on alveolar ridge of the adjacent second molar(M2).</p><p><strong>Methods: </strong>A total of 150 patients who received mandibular impacted M3 extraction in Jinhua Central Hospital from September 2020 to August 2021 were included. Among them, group A (n=49) received conventional suture, group B (n=51)received conventional suture +A-PRF filling, and group C(n=50) received conventional suture +CGF filling. Postoperative clinical indexes, soft tissue healing, alveolar bone density changes and M2 alveolar ridge height changes were compared among the three groups. Meanwhile, complications and adverse reactions were recorded and compared among the three groups. SPSS 20.0 software package was used for data analysis.</p><p><strong>Results: </strong>One week after surgery, the pain degree and swelling degree of the three groups were lower than before treatment(P＜0.05), and group B ＜ group C ＜ group A(P＜0.05). Mouth opening degree was higher than before treatment(P＜0.05), group B ＞ group C ＞ group A (P＜0.05), and the soft tissue healing condition of group B was better than that of group C, and than that of group A(P＜0.05). At 6 weeks and 12 weeks after surgery, the alveolar bone mineral density of the three groups was higher than that immediately after surgery(P＜0.05), and group B ＞ group C ＞ group A(P＜0.05). There were significant differences between group B and C at 6 weeks and 12 weeks after surgery (P＜0.05). The M2 alveolar ridge height (ΔH) 12 days after surgery was lower than that immediately after surgery(P＜0.05), and group B and C was lower than that of group A (P＜0.05). The incidence of complications such as bleeding, infection, dry socket, nerve injury and periodontal pus discharge in group B ＜ group C ＜ group A, and the incidence of complications was statistically significant(P＜0.05).</p><p><strong>Conclusions: </strong>The effects of A-PRF and CGF on M2 alveolar ridge and postoperative adverse reactions are similar, but A-PRF is better than CGF in improving clinical symptoms and promoting postoperative recovery in maxillary impacted M3 patients, with fewer complications, and is worthy of clinical promotion.</p>","PeriodicalId":21709,"journal":{"name":"上海口腔医学","volume":"34 1","pages":"94-99"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Comparison of the effect of A-PRF and CGF on the recovery of mandibular impacted third molar after extraction and on alveolar ridge of the adjacent second molar].\",\"authors\":\"Li-Li Pu, Chun-Hui Chen, Xi Tong\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To compare the recovery effect of advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) in the treatment of mandibular impacted third molar(M3) extraction, and the effect on alveolar ridge of the adjacent second molar(M2).</p><p><strong>Methods: </strong>A total of 150 patients who received mandibular impacted M3 extraction in Jinhua Central Hospital from September 2020 to August 2021 were included. Among them, group A (n=49) received conventional suture, group B (n=51)received conventional suture +A-PRF filling, and group C(n=50) received conventional suture +CGF filling. Postoperative clinical indexes, soft tissue healing, alveolar bone density changes and M2 alveolar ridge height changes were compared among the three groups. Meanwhile, complications and adverse reactions were recorded and compared among the three groups. SPSS 20.0 software package was used for data analysis.</p><p><strong>Results: </strong>One week after surgery, the pain degree and swelling degree of the three groups were lower than before treatment(P＜0.05), and group B ＜ group C ＜ group A(P＜0.05). Mouth opening degree was higher than before treatment(P＜0.05), group B ＞ group C ＞ group A (P＜0.05), and the soft tissue healing condition of group B was better than that of group C, and than that of group A(P＜0.05). At 6 weeks and 12 weeks after surgery, the alveolar bone mineral density of the three groups was higher than that immediately after surgery(P＜0.05), and group B ＞ group C ＞ group A(P＜0.05). There were significant differences between group B and C at 6 weeks and 12 weeks after surgery (P＜0.05). The M2 alveolar ridge height (ΔH) 12 days after surgery was lower than that immediately after surgery(P＜0.05), and group B and C was lower than that of group A (P＜0.05). The incidence of complications such as bleeding, infection, dry socket, nerve injury and periodontal pus discharge in group B ＜ group C ＜ group A, and the incidence of complications was statistically significant(P＜0.05).</p><p><strong>Conclusions: </strong>The effects of A-PRF and CGF on M2 alveolar ridge and postoperative adverse reactions are similar, but A-PRF is better than CGF in improving clinical symptoms and promoting postoperative recovery in maxillary impacted M3 patients, with fewer complications, and is worthy of clinical promotion.</p>\",\"PeriodicalId\":21709,\"journal\":{\"name\":\"上海口腔医学\",\"volume\":\"34 1\",\"pages\":\"94-99\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"上海口腔医学\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"上海口腔医学","FirstCategoryId":"3","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Comparison of the effect of A-PRF and CGF on the recovery of mandibular impacted third molar after extraction and on alveolar ridge of the adjacent second molar].
Purpose: To compare the recovery effect of advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF) in the treatment of mandibular impacted third molar(M3) extraction, and the effect on alveolar ridge of the adjacent second molar(M2).
Methods: A total of 150 patients who received mandibular impacted M3 extraction in Jinhua Central Hospital from September 2020 to August 2021 were included. Among them, group A (n=49) received conventional suture, group B (n=51)received conventional suture +A-PRF filling, and group C(n=50) received conventional suture +CGF filling. Postoperative clinical indexes, soft tissue healing, alveolar bone density changes and M2 alveolar ridge height changes were compared among the three groups. Meanwhile, complications and adverse reactions were recorded and compared among the three groups. SPSS 20.0 software package was used for data analysis.
Results: One week after surgery, the pain degree and swelling degree of the three groups were lower than before treatment(P＜0.05), and group B ＜ group C ＜ group A(P＜0.05). Mouth opening degree was higher than before treatment(P＜0.05), group B ＞ group C ＞ group A (P＜0.05), and the soft tissue healing condition of group B was better than that of group C, and than that of group A(P＜0.05). At 6 weeks and 12 weeks after surgery, the alveolar bone mineral density of the three groups was higher than that immediately after surgery(P＜0.05), and group B ＞ group C ＞ group A(P＜0.05). There were significant differences between group B and C at 6 weeks and 12 weeks after surgery (P＜0.05). The M2 alveolar ridge height (ΔH) 12 days after surgery was lower than that immediately after surgery(P＜0.05), and group B and C was lower than that of group A (P＜0.05). The incidence of complications such as bleeding, infection, dry socket, nerve injury and periodontal pus discharge in group B ＜ group C ＜ group A, and the incidence of complications was statistically significant(P＜0.05).
Conclusions: The effects of A-PRF and CGF on M2 alveolar ridge and postoperative adverse reactions are similar, but A-PRF is better than CGF in improving clinical symptoms and promoting postoperative recovery in maxillary impacted M3 patients, with fewer complications, and is worthy of clinical promotion.
期刊介绍：
"Shanghai Journal of Stomatology (SJS)" is a comprehensive academic journal of stomatology directed by Shanghai Jiao Tong University and sponsored by the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. The main columns include basic research, clinical research, column articles, clinical summaries, reviews, academic lectures, etc., which are suitable for reference by clinicians, scientific researchers and teaching personnel at all levels engaged in oral medicine.
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