基质金属蛋白酶抑制剂对两步通用粘接系统牙本质结合强度和耐久性的影响。

Q2 Dentistry
Mohammad Esmaeel Ebrahimi-Chaharom, Aida Moeinian, Mehdi Abed-Kahnamouei, Mehdi Daneshpooy, Mahmoud Bahari
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引用次数: 0

摘要

背景:本研究的目的是研究使用两种基质金属蛋白酶抑制剂(MMPI)对二步通用胶粘剂(G2-BOND通用胶粘剂)牙本质结合强度和耐久性的影响。材料与方法:本研究共取出24颗磨牙,共144颗样本。将牙合面垂直于纵轴切开,露出牙本质。样品分为6组:1组(对照组,蚀刻冲洗(ER)):在ER模式下粘合,不进行MMPI;第2组:与氯己定(CHX)以ER键成键;第3组:与苯扎氯铵(BAC)以ER模式成键;组4 (Control, Self-etch (SE)):在SE模式下键合,没有MMPI;第5组:与CHX以SE模式成键;第6组:与BAC以SE模式连接。采用复合树脂修复整个牙本质表面。每组进一步分为两个亚组,分别进行500次或10,000次热循环。将样品切割成横截面积为1平方毫米的圆柱体,测试微拉伸粘结强度(µTBS)。数据分析采用3-Way方差分析和Games-Howell检验(p< 0.05)。结果:基于MMPI类型、老化方法和蚀刻策略,平均µTBS有统计学差异。对照组的平均µTBS显著低于CHX组和BAC组(P< 0.05)。24小时和ER组的平均µTBS较高(P< 0.001)。老化的影响一致且呈下降趋势(P < 0.05)。结论:牙本质的µTBS随着年龄的增长而减少。然而,与对照组相比,使用MMPI在一定程度上保留了老化后的粘结强度。关键词:万能胶,基质金属蛋白酶,结合强度,氯己定,苯扎氯铵
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Matrix Metalloproteinase Inhibitors on the Dentin Bond Strength and Durability of a Two-Step Universal Adhesive System.

Background: The aim of this study was to investigate the effects of using two types of matrix metalloproteinase inhibitors (MMPI) on the dentin bond strength and durability of a two-step universal adhesive (G2-BOND Universal Adhesive).

Material and methods: This study was conducted on 24 extracted molars, resulting in 144 samples. The occlusal surface of the teeth was cut perpendicularly to the longitudinal axis to expose the dentin. The samples were divided into 6 groups: Group 1 (Control, etch-and-rinse (ER)): bonding in the ER mode without MMPI; Group 2: bonding in the ER mode with chlorhexidine (CHX); Group 3: bonding in the ER mode with benzalkonium chloride (BAC); Group 4 (Control, Self-etch (SE)): bonding in the SE mode without MMPI; Group 5: bonding in the SE mode with CHX; Group 6: bonding in the SE mode with BAC. The entire dentin surface was restored with composite resin. Each group was further divided into two subgroups and either thermocycled for 500 or 10,000 cycles. The samples were cut into cylinders with a one square millimeter cross-sectional area and tested for microtensile bond strength (µTBS). Data was analyzed using 3-Way ANOVA and Games-Howell tests (p< 0.05).

Results: There was a statistically significant difference in the mean µTBS based on the type of MMPI, aging method, and etching strategy. The mean µTBS in the Control group was significantly lower than in the CHX and BAC groups (P< 0.05). The mean µTBS was higher at 24 hours and in the ER group (P< 0.001). The effect of aging was consistent and decreasing (P> 0.05).

Conclusions: The µTBS to dentin decreases after aging. However, the use of MMPI preserves bond strength to some extent in comparison to control groups after aging. Key words:Universal adhesive, Matrix metalloproteinase, Bond strength, Chlorhexidine, Benzalkonium chloride.

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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
118
期刊介绍: Indexed in PUBMED, PubMed Central® (PMC) since 2012 and SCOPUSJournal of Clinical and Experimental Dentistry is an Open Access (free access on-line) - http://www.medicinaoral.com/odo/indice.htm. The aim of the Journal of Clinical and Experimental Dentistry is: - Periodontology - Community and Preventive Dentistry - Esthetic Dentistry - Biomaterials and Bioengineering in Dentistry - Operative Dentistry and Endodontics - Prosthetic Dentistry - Orthodontics - Oral Medicine and Pathology - Odontostomatology for the disabled or special patients - Oral Surgery
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