德国SPECT和PET神经成像的现状:德国2023年第一次核神经成像调查结果。

Ralph Buchert, Alexander Drzezga, Mathias Schreckenberger, Karl Josef Langen, Philipp T Meyer
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引用次数: 0

摘要

神经退行性疾病的疾病修饰疗法的出现可能导致对核神经成像程序的需求不断增长,这给核医学界带来了机遇,但也带来了挑战。德国的能力和专业知识是否足以满足对核神经成像日益增长的需求正在讨论中。在此背景下,德国核医学学会神经影像学工作组于2023年发起了德国第一次核神经影像学现状调查。参与调查的机构有82家:实践医院33家,社区医院15家,大学医院34家。主要发现如下。在实践中,与医院相比,脑部扫描的频率更低,而且通常仅限于多巴胺转运体SPECT。脑PET主要在医院进行,在社区医院往往仅限于FDG PET。然而,具有良好质量认证的淀粉样PET的可用性是理所当然的。因此,获得淀粉样PET将不会是阿尔茨海默病新疗法的主要瓶颈。在德国,足够的补偿和明确的临床指南锚定具有最大的潜力来推进核神经成像。临床多巴胺转运体SPECT在很大程度上与手术指南一致。一个需要改进的领域是MR图像的有限可用性,以避免将结构/血管病变误解为黑质纹状体变性。该调查提供了德国核神经成像状况的第一个系统评估。它强调了德国核医学社区的能力,以满足日益增长的神经成像程序的需求,其遵守程序指南,并确定了需要改进的主题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Status of Neuroimaging with SPECT and PET in Germany: Results from the 1st Survey on Nuclear Neuroimaging in Germany in 2023.

The advent of disease-modifying therapies for neurodegenerative diseases may result in a growing demand for nuclear neuroimaging procedures presenting opportunities but also challenges to the nuclear medicine community. Whether capacity and expertise in Germany are sufficient to meet an increasing demand for nuclear neuroimaging is under discussion. Against this background, the Neuroimaging Working Group of the German Society of Nuclear Medicine initiated the first survey on the status of nuclear neuroimaging in Germany in 2023. 82 institutions participated in the survey: 33 practices, 15 community hospitals, 34 university hospitals. Primary findings were the following. In practices, brain scans are less frequently performed than in hospitals and are often limited to dopamine transporter SPECT. Brain PET is mainly performed in hospitals, and in community hospitals it is often restricted to FDG PET. Nevertheless, availability of amyloid PET with well-certified quality can be taken for granted. Thus, access to amyloid PET will not be a major bottleneck for new treatments of Alzheimer's disease. Adequate reimbursement and clear anchoring in clinical guidelines have the greatest potential to advance nuclear neuroimaging in Germany. Clinical dopamine transporter SPECT is largely in agreement with procedure guidelines. An area for improvement is the limited availability of MR images to avoid misinterpretation of structural/vascular lesions as nigrostriatal degeneration. The survey provides the first systematic assessment of the status of nuclear neuroimaging in Germany. It underscores the capacity of the German nuclear medicine community to meet an increasing demand for neuroimaging procedures, its adherence to procedure guidelines and identifies topics for improvement.

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