{"title":"支气管内瓣膜-尸检时应考虑的咯血的医源性原因。","authors":"Erin MacDonald, Neil E I Langlois, Roger W Byard","doi":"10.1007/s12024-025-01009-4","DOIUrl":null,"url":null,"abstract":"<p><p>An 80-year-old man who presented with hemoptysis died from ischemic heart disease and emphysema with cor pulmonale. He had a past history of ischemic heart disease with previous myocardial infarction, chronic obstructive pulmonary disease with endobronchial valve insertion and squamous cell carcinoma of the lung with lobe resection. On the day of death he had coughed up approximately one tablespoon of blood. While causes of hemoptysis usually include entities such as bronchitis, pneumonia, bronchiectasis, tumors, adjacent aneurysms, inflammatory/infective processes or septic emboli, occasionally there may be an iatrogenic etiology. The present case demonstrates a rare cause of hemoptysis associated with medical treatment - endobronchial valve insertion with surrounding granulation tissue formation and resultant hemorrhage. Hemoptysis in decedents with COPD may, therefore, be due to treatment rather than to underlying inflammatory or neoplastic lesions.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Endobronchial valves- an iatrogenic cause of hemoptysis to be considered at autopsy.\",\"authors\":\"Erin MacDonald, Neil E I Langlois, Roger W Byard\",\"doi\":\"10.1007/s12024-025-01009-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An 80-year-old man who presented with hemoptysis died from ischemic heart disease and emphysema with cor pulmonale. He had a past history of ischemic heart disease with previous myocardial infarction, chronic obstructive pulmonary disease with endobronchial valve insertion and squamous cell carcinoma of the lung with lobe resection. On the day of death he had coughed up approximately one tablespoon of blood. While causes of hemoptysis usually include entities such as bronchitis, pneumonia, bronchiectasis, tumors, adjacent aneurysms, inflammatory/infective processes or septic emboli, occasionally there may be an iatrogenic etiology. The present case demonstrates a rare cause of hemoptysis associated with medical treatment - endobronchial valve insertion with surrounding granulation tissue formation and resultant hemorrhage. Hemoptysis in decedents with COPD may, therefore, be due to treatment rather than to underlying inflammatory or neoplastic lesions.</p>\",\"PeriodicalId\":12449,\"journal\":{\"name\":\"Forensic Science, Medicine and Pathology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forensic Science, Medicine and Pathology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12024-025-01009-4\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, LEGAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic Science, Medicine and Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12024-025-01009-4","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, LEGAL","Score":null,"Total":0}
Endobronchial valves- an iatrogenic cause of hemoptysis to be considered at autopsy.
An 80-year-old man who presented with hemoptysis died from ischemic heart disease and emphysema with cor pulmonale. He had a past history of ischemic heart disease with previous myocardial infarction, chronic obstructive pulmonary disease with endobronchial valve insertion and squamous cell carcinoma of the lung with lobe resection. On the day of death he had coughed up approximately one tablespoon of blood. While causes of hemoptysis usually include entities such as bronchitis, pneumonia, bronchiectasis, tumors, adjacent aneurysms, inflammatory/infective processes or septic emboli, occasionally there may be an iatrogenic etiology. The present case demonstrates a rare cause of hemoptysis associated with medical treatment - endobronchial valve insertion with surrounding granulation tissue formation and resultant hemorrhage. Hemoptysis in decedents with COPD may, therefore, be due to treatment rather than to underlying inflammatory or neoplastic lesions.
期刊介绍:
Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.