主动脉血管肉瘤致截瘫1例。

IF 2.8 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Frontiers in Cardiovascular Medicine Pub Date : 2025-04-29 eCollection Date: 2025-01-01 DOI:10.3389/fcvm.2025.1551262
Jing Li, Jiubo Sun
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引用次数: 0

摘要

背景:主动脉血管肉瘤是一种临床症状不典型的罕见疾病。它最初通常表现为栓塞现象,如下肢动脉栓塞、内脏栓塞或脑栓塞,或肾血管性高血压。方法:文献中未见由此病引起的脊髓栓塞病例报道。我们报告一例76岁的女性患者,其腹部CT显示左侧髋关节软组织肿块,累及骶骨和髂骨。结果:主动脉CTA显示主动脉弓和降主动脉不规则充盈缺损,高度提示肿瘤。左髋肿块的活检证实了血管肉瘤的诊断。免疫组化结果为Vimentin、CD31、ERG阳性。根据患者的CTA表现,诊断为主动脉血管肉瘤并左髋关节软组织转移。患者出现截瘫和下肢动脉栓塞,不久后死亡。本文就有关主动脉血管肉瘤的文献作一综述。结论:本病例报告的目的是强调在临床实践中监测常见栓塞部位的重要性,同时也考虑到罕见部位的可能性,如脊髓栓塞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aortic angiosarcoma leading to paraplegia: a case report.

Background: Aortic angiosarcoma is a rare disease with atypical clinical symptoms. It often initially presents with embolic phenomena, such as lower limb arterial embolism, visceral embolism, or cerebral embolism, or as renovascular hypertension.

Methods: There are no reported cases in the literature of spinal cord embolism caused by this condition. We report a case of a 76-year-old female patient whose abdominal CT showed a soft tissue mass in the left hip, involving the sacrum and iliac bone.

Results: Aortic CTA revealed irregular filling defects in the aortic arch and descending aorta, highly suggestive of a tumor. A biopsy of the left hip mass confirmed the diagnosis of angiosarcoma. Immunohistochemistry results were positive for Vimentin, CD31, and ERG. Based on the patient's CTA findings, a diagnosis of aortic angiosarcoma with left hip soft tissue metastasis was made. The patient developed paraplegia and lower limb arterial embolism and died shortly afterward. This article briefly reviews the literature on aortic angiosarcoma.

Conclusions: The purpose of this case report is to highlight the importance of monitoring common embolic sites in clinical practice, while also considering the possibility of rare sites, such as spinal cord embolism.

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来源期刊
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.80
自引率
11.10%
发文量
3529
审稿时长
14 weeks
期刊介绍: Frontiers? Which frontiers? Where exactly are the frontiers of cardiovascular medicine? And who should be defining these frontiers? At Frontiers in Cardiovascular Medicine we believe it is worth being curious to foresee and explore beyond the current frontiers. In other words, we would like, through the articles published by our community journal Frontiers in Cardiovascular Medicine, to anticipate the future of cardiovascular medicine, and thus better prevent cardiovascular disorders and improve therapeutic options and outcomes of our patients.
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