Tran Ba Lan, Cao Hoai Tuan Anh, Thi Lan Anh Nguyen, Tran Diep Khoa, Nguyen Hoang Thien Thu, Nguyen Quynh Truc, Minh Huu Le, Quoc Si Huynh, Tuyen Thi Hong Nguyen
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Short-term mortality was defined as death within 30 days of onset.</p><p><strong>Results: </strong>Among the 598 patients (mean age 58.4; 40% female), 110 (18.4%) died, while 488 (81.6%) survived. The ICH score (AUC = 95.75%; <i>p</i> < 0.001; optimal cutoff = 1.5) was more prognostic for mortality than the NIHSS score (AUC = 94.61%; optimal cutoff = 17.5; <i>p</i> < 0.001). Identified risk factors included age ≥ 80 (RR = 2.2, <i>p</i> = 0.002), ICH score ≥ 2 (RR = 38.4, <i>p</i> < 0.001), NIHSS score ≥ 16 (RR = 15.1, <i>p</i> < 0.001), hematoma volume ≥ 30 cm<sup>3</sup> (RR = 15.1, <i>p</i> < 0.001), and the presence of intraventricular (RR = 7.2, <i>p</i> < 0.001) or subtentorial hemorrhage (RR = 2.8, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The mortality rate for ICH was significant. The ICH score, NIHSS, and hematoma volume are effective in predicting mortality in spontaneous ICH patients.</p>","PeriodicalId":45958,"journal":{"name":"Journal of Public Health Research","volume":"14 2","pages":"22799036251334178"},"PeriodicalIF":1.8000,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033613/pdf/","citationCount":"0","resultStr":"{\"title\":\"Short-term mortality prognosis in spontaneous intracranial hemorrhage: A retrospective study at 115 People's Hospital, HCMC, Vietnam.\",\"authors\":\"Tran Ba Lan, Cao Hoai Tuan Anh, Thi Lan Anh Nguyen, Tran Diep Khoa, Nguyen Hoang Thien Thu, Nguyen Quynh Truc, Minh Huu Le, Quoc Si Huynh, Tuyen Thi Hong Nguyen\",\"doi\":\"10.1177/22799036251334178\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Early prognosis of patients with spontaneous intracerebral hemorrhage (ICH) can help create individualized and optimized treatment plans for the patients.</p><p><strong>Aims: </strong>This study evaluates short-term mortality and identifies risk factors in ICH patients at 115 People's Hospital within 30 days.</p><p><strong>Design and methods: </strong>A retrospective cohort study was conducted involving 598 patients diagnosed with ICH by neurologists from December 2022 to June 2023. Diagnosis was confirmed by imaging, with symptoms appearing within 24 h of admission. Short-term mortality was defined as death within 30 days of onset.</p><p><strong>Results: </strong>Among the 598 patients (mean age 58.4; 40% female), 110 (18.4%) died, while 488 (81.6%) survived. The ICH score (AUC = 95.75%; <i>p</i> < 0.001; optimal cutoff = 1.5) was more prognostic for mortality than the NIHSS score (AUC = 94.61%; optimal cutoff = 17.5; <i>p</i> < 0.001). Identified risk factors included age ≥ 80 (RR = 2.2, <i>p</i> = 0.002), ICH score ≥ 2 (RR = 38.4, <i>p</i> < 0.001), NIHSS score ≥ 16 (RR = 15.1, <i>p</i> < 0.001), hematoma volume ≥ 30 cm<sup>3</sup> (RR = 15.1, <i>p</i> < 0.001), and the presence of intraventricular (RR = 7.2, <i>p</i> < 0.001) or subtentorial hemorrhage (RR = 2.8, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The mortality rate for ICH was significant. The ICH score, NIHSS, and hematoma volume are effective in predicting mortality in spontaneous ICH patients.</p>\",\"PeriodicalId\":45958,\"journal\":{\"name\":\"Journal of Public Health Research\",\"volume\":\"14 2\",\"pages\":\"22799036251334178\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033613/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Public Health Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/22799036251334178\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Public Health Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/22799036251334178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
背景：自发性脑出血患者的早期预后有助于为患者制定个性化和优化的治疗方案。目的：本研究评估115人民医院脑出血患者30天内的短期死亡率并确定危险因素。设计和方法：一项回顾性队列研究，纳入了598例由神经科医生诊断为脑出血的患者，时间为2022年12月至2023年6月。经影像学确诊，入院24小时内出现症状。短期死亡率定义为发病后30天内死亡。结果：598例患者中，平均年龄58.4岁；死亡110例（18.4%），存活488例（81.6%）。ICH评分(AUC = 95.75%；p p = 0.002)， ICH评分≥2 （RR = 38.4, RR = 15.1, p p p p）。脑出血评分、NIHSS和血肿体积可有效预测自发性脑出血患者的死亡率。
Short-term mortality prognosis in spontaneous intracranial hemorrhage: A retrospective study at 115 People's Hospital, HCMC, Vietnam.
Background: Early prognosis of patients with spontaneous intracerebral hemorrhage (ICH) can help create individualized and optimized treatment plans for the patients.
Aims: This study evaluates short-term mortality and identifies risk factors in ICH patients at 115 People's Hospital within 30 days.
Design and methods: A retrospective cohort study was conducted involving 598 patients diagnosed with ICH by neurologists from December 2022 to June 2023. Diagnosis was confirmed by imaging, with symptoms appearing within 24 h of admission. Short-term mortality was defined as death within 30 days of onset.
Results: Among the 598 patients (mean age 58.4; 40% female), 110 (18.4%) died, while 488 (81.6%) survived. The ICH score (AUC = 95.75%; p < 0.001; optimal cutoff = 1.5) was more prognostic for mortality than the NIHSS score (AUC = 94.61%; optimal cutoff = 17.5; p < 0.001). Identified risk factors included age ≥ 80 (RR = 2.2, p = 0.002), ICH score ≥ 2 (RR = 38.4, p < 0.001), NIHSS score ≥ 16 (RR = 15.1, p < 0.001), hematoma volume ≥ 30 cm3 (RR = 15.1, p < 0.001), and the presence of intraventricular (RR = 7.2, p < 0.001) or subtentorial hemorrhage (RR = 2.8, p < 0.001).
Conclusions: The mortality rate for ICH was significant. The ICH score, NIHSS, and hematoma volume are effective in predicting mortality in spontaneous ICH patients.
期刊介绍：
The Journal of Public Health Research (JPHR) is an online Open Access, peer-reviewed journal in the field of public health science. The aim of the journal is to stimulate debate and dissemination of knowledge in the public health field in order to improve efficacy, effectiveness and efficiency of public health interventions to improve health outcomes of populations. This aim can only be achieved by adopting a global and multidisciplinary approach. The Journal of Public Health Research publishes contributions from both the “traditional'' disciplines of public health, including hygiene, epidemiology, health education, environmental health, occupational health, health policy, hospital management, health economics, law and ethics as well as from the area of new health care fields including social science, communication science, eHealth and mHealth philosophy, health technology assessment, genetics research implications, population-mental health, gender and disparity issues, global and migration-related themes. In support of this approach, JPHR strongly encourages the use of real multidisciplinary approaches and analyses in the manuscripts submitted to the journal. In addition to Original research, Systematic Review, Meta-analysis, Meta-synthesis and Perspectives and Debate articles, JPHR publishes newsworthy Brief Reports, Letters and Study Protocols related to public health and public health management activities.
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