{"title":"比较评价硅酸钙和生物活性玻璃基与环氧树脂基密封剂根管封闭术后疼痛和愈合：一项系统回顾和荟萃分析。","authors":"Vibha Rahul Hegde, Sanitra Rahul Hegde, Ushaina Eruch Fanibunda, Meghana Aditya Vartak","doi":"10.4103/JCDE.JCDE_8_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To compare the postoperative pain and healing following obturation with calcium silicate and bioactive glass-based sealers to epoxy resin sealers.</p><p><strong>Materials and methods: </strong>A systematic search (2018-2024) was conducted using PubMed, Cochrane, and Google Scholar, following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (PRISMA). Risk of bias (RoB) was assessed using Cochrane RoB 2 tool and quality was evaluated using GRADE. Twenty-three studies were included for qualitative analysis and 11 for quantitative analysis, including meta-analysis for bioactive glass and epoxy resin-based sealers.</p><p><strong>Results: </strong>Meta-analysis revealed no significant difference in pain occurrence between groups at 24 h, 48 h, and 7 days. Similarly, for bioactive glass sealer, no significant difference in pain occurrence was observed at 24 h, 48 h, and 7 days.</p><p><strong>Conclusion: </strong>Calcium-silicate-based sealers showed comparable and satisfactory results to epoxy resin sealers regarding postoperative pain incidence and intensity. In addition, they facilitated improved healing of periapical tissues. Notably, bioactive glass-based sealer also demonstrated exceptional properties, offering enhanced benefits.</p>","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 3","pages":"211-221"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007741/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparative evaluation of postoperative pain and healing following root canal obturation with calcium silicate and bioactive glass-based sealers to epoxy resin-based sealers: A systematic review and meta-analysis.\",\"authors\":\"Vibha Rahul Hegde, Sanitra Rahul Hegde, Ushaina Eruch Fanibunda, Meghana Aditya Vartak\",\"doi\":\"10.4103/JCDE.JCDE_8_25\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To compare the postoperative pain and healing following obturation with calcium silicate and bioactive glass-based sealers to epoxy resin sealers.</p><p><strong>Materials and methods: </strong>A systematic search (2018-2024) was conducted using PubMed, Cochrane, and Google Scholar, following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (PRISMA). Risk of bias (RoB) was assessed using Cochrane RoB 2 tool and quality was evaluated using GRADE. Twenty-three studies were included for qualitative analysis and 11 for quantitative analysis, including meta-analysis for bioactive glass and epoxy resin-based sealers.</p><p><strong>Results: </strong>Meta-analysis revealed no significant difference in pain occurrence between groups at 24 h, 48 h, and 7 days. Similarly, for bioactive glass sealer, no significant difference in pain occurrence was observed at 24 h, 48 h, and 7 days.</p><p><strong>Conclusion: </strong>Calcium-silicate-based sealers showed comparable and satisfactory results to epoxy resin sealers regarding postoperative pain incidence and intensity. In addition, they facilitated improved healing of periapical tissues. Notably, bioactive glass-based sealer also demonstrated exceptional properties, offering enhanced benefits.</p>\",\"PeriodicalId\":516842,\"journal\":{\"name\":\"Journal of conservative dentistry and endodontics\",\"volume\":\"28 3\",\"pages\":\"211-221\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007741/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of conservative dentistry and endodontics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/JCDE.JCDE_8_25\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of conservative dentistry and endodontics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/JCDE.JCDE_8_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/3 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的：比较硅酸钙和生物活性玻璃基密封剂与环氧树脂密封剂的术后疼痛和愈合情况。材料和方法：根据系统评价和荟萃分析指南的首选报告项目（PRISMA），使用PubMed、Cochrane和谷歌Scholar进行了系统检索（2018-2024）。使用Cochrane RoB 2工具评估偏倚风险（RoB），使用GRADE评估质量。23项研究用于定性分析，11项用于定量分析，包括生物活性玻璃和环氧树脂基密封剂的荟萃分析。结果：meta分析显示，两组在24 h、48 h和7天的疼痛发生率无显著差异。同样，对于生物活性玻璃密封剂，24小时、48小时和7天疼痛发生率无显著差异。结论：在术后疼痛发生率和强度方面，硅酸钙基密封剂与环氧树脂密封剂的效果相当且令人满意。此外，它们还促进了根尖周围组织的愈合。值得注意的是，生物活性玻璃基封口剂也表现出卓越的性能，提供增强的好处。
Comparative evaluation of postoperative pain and healing following root canal obturation with calcium silicate and bioactive glass-based sealers to epoxy resin-based sealers: A systematic review and meta-analysis.
Aim: To compare the postoperative pain and healing following obturation with calcium silicate and bioactive glass-based sealers to epoxy resin sealers.
Materials and methods: A systematic search (2018-2024) was conducted using PubMed, Cochrane, and Google Scholar, following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (PRISMA). Risk of bias (RoB) was assessed using Cochrane RoB 2 tool and quality was evaluated using GRADE. Twenty-three studies were included for qualitative analysis and 11 for quantitative analysis, including meta-analysis for bioactive glass and epoxy resin-based sealers.
Results: Meta-analysis revealed no significant difference in pain occurrence between groups at 24 h, 48 h, and 7 days. Similarly, for bioactive glass sealer, no significant difference in pain occurrence was observed at 24 h, 48 h, and 7 days.
Conclusion: Calcium-silicate-based sealers showed comparable and satisfactory results to epoxy resin sealers regarding postoperative pain incidence and intensity. In addition, they facilitated improved healing of periapical tissues. Notably, bioactive glass-based sealer also demonstrated exceptional properties, offering enhanced benefits.
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