饲料中的真菌毒素:危害、毒理学和基于植物提取物的补救措施。

IF 3.4 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Metabolites Pub Date : 2025-03-24 DOI:10.3390/metabo15040219
Xiangnan Zhang, Jiashun Chen, Xiaokang Ma, Xiongzhuo Tang, Bie Tan, Peng Liao, Kang Yao, Qian Jiang
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引用次数: 0

摘要

背景:真菌毒素是真菌产生的次生代谢产物,普遍存在于动物饲料中,对畜禽的健康生长构成严重威胁。方法:本综述旨在总结真菌毒素对动物健康有害影响的现有知识,并证明植物提取物作为一种抵消饲料中真菌毒素毒性的手段的潜力。对文献进行了系统回顾,以确定真菌毒素对牲畜和家禽健康影响的研究,以及使用植物提取物作为饲料添加剂以减轻真菌毒素影响的研究。根据与主题的相关性选择研究,并提取有关植物提取物的作用机制和功效的数据。结果:饲料中过量的真菌毒素可导致动物食欲下降、消化受损和一般健康问题,导致食物摄入量减少、体重增加缓慢和急性中毒。具有抗氧化、抗炎和抗诱变特性的植物提取物已显示出提高生产效率和减少真菌毒素毒性作用的潜力。结论:这篇全面的综述不仅巩固了真菌毒素对动物健康的不良影响,而且通过强调植物提取物作为对抗真菌毒素毒性的有前途的天然解决方案的潜力,引入了一个新的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mycotoxins in Feed: Hazards, Toxicology, and Plant Extract-Based Remedies.

Background: Mycotoxins, which are secondary metabolites produced by fungi, are prevalent in animal feed and pose a serious risk to the healthy growth of livestock and poultry. Methods: This review aims to conclude current knowledge on the detrimental effects of mycotoxins on animal health and to demonstrate the potential of plant extracts as a means to counteract mycotoxin toxicity in feed. A systematic review of the literature was conducted to identify studies on the impact of mycotoxins on livestock and poultry health, as well as research into the use of plant extracts as feed additives to mitigate mycotoxin effects. Studies were selected based on their relevance to the topic, and data were extracted regarding the mechanisms of action and the efficacy of plant extracts. Results: Excessive mycotoxins in feed can lead to reduced appetite, impaired digestion, and general health issues in animals, resulting in decreased food intake, slowed weight gain, and instances of acute poisoning. Plant extracts with antioxidant, anti-inflammatory, and anti-mutagenic properties have shown the potential to improve production efficiency and reduce the toxic effects of mycotoxins. Conclusion: This comprehensive review not only consolidates the well-documented adverse effects of mycotoxins on animal health but also introduces a novel perspective by highlighting the potential of plant extracts as a promising and natural solution to counteract mycotoxin toxicity.

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来源期刊
Metabolites
Metabolites Biochemistry, Genetics and Molecular Biology-Molecular Biology
CiteScore
5.70
自引率
7.30%
发文量
1070
审稿时长
17.17 days
期刊介绍: Metabolites (ISSN 2218-1989) is an international, peer-reviewed open access journal of metabolism and metabolomics. Metabolites publishes original research articles and review articles in all molecular aspects of metabolism relevant to the fields of metabolomics, metabolic biochemistry, computational and systems biology, biotechnology and medicine, with a particular focus on the biological roles of metabolites and small molecule biomarkers. Metabolites encourages scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on article length. Sufficient experimental details must be provided to enable the results to be accurately reproduced. Electronic material representing additional figures, materials and methods explanation, or supporting results and evidence can be submitted with the main manuscript as supplementary material.
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