腹膜透析在挑战腹部:回顾审查肥胖和粘连的作用。

IF 2.7 3区 医学 Q2 UROLOGY & NEPHROLOGY
Michael Ghio, Aaron Albuck, Phoebe Huang, Mahmoud Omar, Anil Paramesh
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引用次数: 0

摘要

腹膜透析(PD)是终末期肾病患者越来越常见的治疗方式。腹腔镜腹膜透析导管放置(LPDC)可能会使被认为腹部困难的PD患者获得成功的结果。方法回顾性分析2009年7月至2024年5月由同一位外科医生连续行LPDC的505例患者。评估有/无合并症患者的术中决策和并发症发生率。风险比计算采用Cox回归,p值计算采用SPSS。结果研究人群平均年龄为53.4±14.8岁,女性占45.1% (n = 228),黑人占60.2% (n = 304)。平均BMI为31.7±7.3。192例患者(57.8%)既往有腹部手术史。13例(2.6%)患者不能安全进行LPDC。186例(36.8%)患者需要在初始放置时解除粘连。BMI低于35 kg/m2不会增加修订的风险,风险比(HR)为0.9(0.6-1.4)。粘连溶解不增加修订的风险(HR 1.3(0.9-1.9))。122例(24.7%)患者出现导管相关并发症,需要翻修。导管相关并发症在粘连松解组(n = 104, 21.1%)和未粘连松解组(n = 91, 18.5%, P < 0.05)之间无显著差异。492例患者中有35例(7.1%)需要两次或两次以上的翻修。1年改良通畅率为94.1%(446/474)。结论:这是LPDC中最大的单外科手术经验之一。腹腔镜技术有助于为腹部困难和肥胖患者提供长期透析的可行选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Peritoneal dialysis in the challenging abdomen: A retrospective review examining the role of obesity and adhesions.

BackgroundPeritoneal dialysis (PD) is an increasingly common modality for end-stage kidney disease patients. Laparoscopic peritoneal dialysis catheter placement (LPDC) may allow for successful outcomes in patients considered to have difficult abdomens for PD.MethodsThis was a retrospective review of 505 consecutive patients who underwent attempted LPDC between July 2009 and May 2024 by a single surgeon. Intraoperative decision making and rate of complications were evaluated in patients with/without comorbidities. Hazard ratio calculations using Cox regression and P-values were calculated using SPSS.ResultsAverage age of the study population is 53.4 ± 14.8 years, 45.1% (n = 228) were female, and 60.2% (n = 304) were Black. Average BMI was 31.7 ± 7.3. Two hundred ninety-two patients (57.8%) had previous abdominal surgery. LPDC could not be done safely in 13 patients (2.6%). Lysis of adhesions at initial placement was needed in 186 patients (36.8%). BMI > 35 kg/m2 did not increase the risk of revision with a hazard ratio (HR) of 0.9 (0.6-1.4). Adhesiolysis did not increase the risk of revision (HR 1.3 (0.9-1.9)). Catheter-related complications required revision in 122 patients (24.7%). Catheter-related complications did not vary significantly between those who had (n = 104, 21.1%) and had not had adhesiolysis (n = 91, 18.5%, P > .05). Two or more revisions were required in 35/492(7.1%) patients. One-year modified patency rate was 94.1% (446/474).ConclusionThis represents one of the largest reported single surgeon experiences in LPDC. Laparoscopic techniques can help provide a feasible option for long-term dialysis in patients with a difficult abdomen and the disease of obesity.

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来源期刊
Peritoneal Dialysis International
Peritoneal Dialysis International 医学-泌尿学与肾脏学
CiteScore
6.00
自引率
17.90%
发文量
69
审稿时长
6-12 weeks
期刊介绍: Peritoneal Dialysis International (PDI) is an international publication dedicated to peritoneal dialysis. PDI welcomes original contributions dealing with all aspects of peritoneal dialysis from scientists working in the peritoneal dialysis field around the world. Peritoneal Dialysis International is included in Index Medicus and indexed in Current Contents/Clinical Practice, the Science Citation Index, and Excerpta Medica (Nephrology/Urology Core Journal). It is also abstracted and indexed in Chemical Abstracts (CA), as well as being indexed in Embase as a priority journal.
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