犬胚胎特征的高级别少突胶质细胞瘤的细胞学和组织学研究。

IF 1.1 3区 农林科学 Q3 VETERINARY SCIENCES
Flavio H Alonso, Aria Phan, Kelly O'Connell, Demitria M Vasilatis
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引用次数: 0

摘要

一个10岁的阉割雄性德国线导犬被提出转诊评估脑肿块和开颅手术。相关病史包括急性发作的丛集性癫痫发作;全身体格检查基本上没有什么特别之处。彻底的实验室和影像学检查排除了出现临床症状的颅外原因。核磁共振显示左额叶出血和强对比增强肿块。开颅后,病变为周围有苹果酸组织的异常皮质实质,切除并提交显微镜分析。肿块的挤压准备的细胞学检查显示轻度炎症和出血性肿瘤,少突胶质细胞瘤或胚胎性中枢神经系统肿瘤作为主要鉴别诊断。免疫组织化学病理证实为胚胎形态的高级别少突胶质细胞瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cytology and histology of a high-grade oligodendroglioma with embryonal features in a dog.

A 10-y-old castrated male German Wirehaired Pointer dog was presented for referral evaluation of a brain mass and craniotomy. Pertinent history included acute onset of cluster seizures; the systemic physical examination was largely unremarkable. Thorough laboratory and imaging screening ruled out extracranial causes for the presenting clinical signs. MRI revealed a hemorrhagic and strongly contrast-enhancing mass in the left frontal lobe. Upon craniotomy, the lesion was abnormal cortical parenchyma with surrounding malacic tissue, which was excised and submitted for microscopic analyses. Cytologic examination of a squash preparation of the mass revealed a mildly inflamed and hemorrhagic neoplasm, with oligodendroglioma or an embryonal CNS neoplasm as primary differential diagnoses. Histopathology with immunohistochemistry confirmed a high-grade oligodendroglioma with embryonal morphology.

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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
127
审稿时长
6-16 weeks
期刊介绍: The Journal of Veterinary Diagnostic Investigation (J Vet Diagn Invest) is an international peer-reviewed journal published bimonthly in English by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). JVDI is devoted to all aspects of veterinary laboratory diagnostic science including the major disciplines of anatomic pathology, bacteriology/mycology, clinical pathology, epidemiology, immunology, laboratory information management, molecular biology, parasitology, public health, toxicology, and virology.
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