Lauren T. Roland, Cecelia Damask, Amber U. Luong, Antoine Azar, Charles S. Ebert Jr., Thomas Edwards, Katherine N. Cahill, Do-Yeon Cho, David Corry, Tara L. Croston, Alexandra F. Freeman, Amin Javer, Paneez Khoury, Jean Kim, Michael Koval, Edward D. McCoul, James W. Mims, Anju Peters, Jay F. Piccirillo, Richard P. Ramonell, Amali Samarasinghe, Robert P. Schleimer, Prestina Smith-Davidson, Andrej Spec, Michael E. Wechsler, Sarah K. Wise, Joshua M. Levy
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引用次数: 0
摘要
过敏性真菌性鼻鼻窦炎(AFRS)是一种独特的慢性鼻鼻窦炎伴鼻息肉(CRSwNP)。尽管与其他CRSwNP亚型相比,AFRS的复发率高,而且往往表现出更严重的症状,但一直缺乏专门针对AFRS的研究。诊断标准落后,AFRS与其他相关疾病的机制关系尚不清楚,疾病的病理生理及复发危险因素研究尚不充分。2023年12月,一个由鼻科医生、耳鼻喉科医生、肺科医生、过敏症专家、免疫学家、科学家和传染病专家组成的多学科小组在美国国立卫生研究院(National Institute of Health)开会,讨论未来AFRS研究和护理的未满足需求,包括患者管理、诊断标准、严重程度、病理生理学和相关条件。以下是这些临床和相关研究讨论的摘要。
Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop
Allergic fungal rhinosinusitis (AFRS) is a unique endotype of chronic rhinosinusitis with nasal polyps (CRSwNP). Despite high recurrence rates and often more severe presenting signs compared with other subtypes of CRSwNP, research dedicated to AFRS has been lacking. Diagnostic criteria are outdated, the mechanistic relationship of AFRS to other associated diseases is unclear, and the pathophysiology of disease and risk factors for recurrence have not been well studied. In December 2023, a multidisciplinary group of rhinologists, otolaryngologists, pulmonologists, allergists, immunologists, scientists, and infectious disease experts met at the National Institute of Health to discuss unmet needs for future AFRS research and care, including patient management, diagnostic criteria, severity, pathophysiology, and related conditions. A summary of these clinical and associated research discussions is included below.
期刊介绍:
International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy.
International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.