{"title":"枣是一种主要的干果,可以延长隐杆线虫的寿命。","authors":"Koji Kakugawa , Shion Uehara , Syunya Katoh , Naoki Arimatsu , Sho Ogaki , Koji Masumura , Hideki Murakawa , Kenji Arakawa , Masaki Mizunuma","doi":"10.1016/j.jbiosc.2025.04.006","DOIUrl":null,"url":null,"abstract":"<div><div>Dried fruits have many advantages on condensed nutrients, food preservation, and availability through all seasons. This study investigated the longevity effects of five commercially available dried fruits (date, pineapple, fig, mango, and prune) on <em>Caenorhabditis elegans</em>. Each of the five dried fruits remarkably increased the lifespan compared with the control group. Especially, date fruit had the longest mean and maximum lifespan. In the analysis for the ratio of mean lifespan (MLS) to maximum lifespan in order to clarify their relationship, the ratio for date fruit was approximately 0.9, showing that it results in a longer MLS than other dried fruits. These results imply that date fruit consumption leads to a significantly greater increase in the MLS of <em>C</em>. <em>elegans</em>. The date fruit examined in this study did not contain syringic acid, a previously reported factor known to extend lifespan in date fruit, suggesting that other unidentified component(s) may contribute to its longevity-promoting effect.</div></div>","PeriodicalId":15199,"journal":{"name":"Journal of bioscience and bioengineering","volume":"140 1","pages":"Pages 36-41"},"PeriodicalIF":2.9000,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Date, a major dried fruit, extends the lifespan of Caenorhabditis elegans\",\"authors\":\"Koji Kakugawa , Shion Uehara , Syunya Katoh , Naoki Arimatsu , Sho Ogaki , Koji Masumura , Hideki Murakawa , Kenji Arakawa , Masaki Mizunuma\",\"doi\":\"10.1016/j.jbiosc.2025.04.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Dried fruits have many advantages on condensed nutrients, food preservation, and availability through all seasons. This study investigated the longevity effects of five commercially available dried fruits (date, pineapple, fig, mango, and prune) on <em>Caenorhabditis elegans</em>. Each of the five dried fruits remarkably increased the lifespan compared with the control group. Especially, date fruit had the longest mean and maximum lifespan. In the analysis for the ratio of mean lifespan (MLS) to maximum lifespan in order to clarify their relationship, the ratio for date fruit was approximately 0.9, showing that it results in a longer MLS than other dried fruits. These results imply that date fruit consumption leads to a significantly greater increase in the MLS of <em>C</em>. <em>elegans</em>. The date fruit examined in this study did not contain syringic acid, a previously reported factor known to extend lifespan in date fruit, suggesting that other unidentified component(s) may contribute to its longevity-promoting effect.</div></div>\",\"PeriodicalId\":15199,\"journal\":{\"name\":\"Journal of bioscience and bioengineering\",\"volume\":\"140 1\",\"pages\":\"Pages 36-41\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-05-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of bioscience and bioengineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1389172325000866\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of bioscience and bioengineering","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1389172325000866","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Date, a major dried fruit, extends the lifespan of Caenorhabditis elegans
Dried fruits have many advantages on condensed nutrients, food preservation, and availability through all seasons. This study investigated the longevity effects of five commercially available dried fruits (date, pineapple, fig, mango, and prune) on Caenorhabditis elegans. Each of the five dried fruits remarkably increased the lifespan compared with the control group. Especially, date fruit had the longest mean and maximum lifespan. In the analysis for the ratio of mean lifespan (MLS) to maximum lifespan in order to clarify their relationship, the ratio for date fruit was approximately 0.9, showing that it results in a longer MLS than other dried fruits. These results imply that date fruit consumption leads to a significantly greater increase in the MLS of C. elegans. The date fruit examined in this study did not contain syringic acid, a previously reported factor known to extend lifespan in date fruit, suggesting that other unidentified component(s) may contribute to its longevity-promoting effect.
期刊介绍:
The Journal of Bioscience and Bioengineering is a research journal publishing original full-length research papers, reviews, and Letters to the Editor. The Journal is devoted to the advancement and dissemination of knowledge concerning fermentation technology, biochemical engineering, food technology and microbiology.