Kuan-Chi Lai, Laura M Walker, Kevin Moran, Jordan W Swanson, Jesse A Taylor, Janet Lioy, Christopher M Cielo
{"title":"小颌畸形婴儿的短期和四年喂养和呼吸结局。","authors":"Kuan-Chi Lai, Laura M Walker, Kevin Moran, Jordan W Swanson, Jesse A Taylor, Janet Lioy, Christopher M Cielo","doi":"10.1038/s41372-025-02224-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To describe feeding and respiratory outcomes at discharge and at the most recent follow-up visit prior to four years old in infants evaluated for micrognathia.</p><p><strong>Study design: </strong>Single-center retrospective analysis of 218 patients admitted and evaluated with congenital micrognathia during infancy. Outcomes were compared based on treatment (medical, mandibular distraction osteogenesis, or tracheostomy), and also compared based on syndromic status.</p><p><strong>Results: </strong>Tube feeding was required by 81% of infants at discharge and 41% at follow-up. Respiratory support was required by 32% at discharge and 22% at follow-up. There were no differences in feeding and respiratory support at discharge and at follow-up between medical treatment and mandibular distraction osteogenesis. Tracheostomy was associated with more tube feeding and respiratory support at both discharge and at follow-up. Genetic syndromes were more likely to require tube feeding and respiratory support.</p><p><strong>Conclusion: </strong>Long-term feeding and respiratory support are common in infants hospitalized with micrognathia.</p>","PeriodicalId":16690,"journal":{"name":"Journal of Perinatology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Short-term and four-year feeding and respiratory outcomes of infants with micrognathia.\",\"authors\":\"Kuan-Chi Lai, Laura M Walker, Kevin Moran, Jordan W Swanson, Jesse A Taylor, Janet Lioy, Christopher M Cielo\",\"doi\":\"10.1038/s41372-025-02224-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To describe feeding and respiratory outcomes at discharge and at the most recent follow-up visit prior to four years old in infants evaluated for micrognathia.</p><p><strong>Study design: </strong>Single-center retrospective analysis of 218 patients admitted and evaluated with congenital micrognathia during infancy. Outcomes were compared based on treatment (medical, mandibular distraction osteogenesis, or tracheostomy), and also compared based on syndromic status.</p><p><strong>Results: </strong>Tube feeding was required by 81% of infants at discharge and 41% at follow-up. Respiratory support was required by 32% at discharge and 22% at follow-up. There were no differences in feeding and respiratory support at discharge and at follow-up between medical treatment and mandibular distraction osteogenesis. Tracheostomy was associated with more tube feeding and respiratory support at both discharge and at follow-up. Genetic syndromes were more likely to require tube feeding and respiratory support.</p><p><strong>Conclusion: </strong>Long-term feeding and respiratory support are common in infants hospitalized with micrognathia.</p>\",\"PeriodicalId\":16690,\"journal\":{\"name\":\"Journal of Perinatology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-04-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Perinatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41372-025-02224-1\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Perinatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41372-025-02224-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Short-term and four-year feeding and respiratory outcomes of infants with micrognathia.
Objective: To describe feeding and respiratory outcomes at discharge and at the most recent follow-up visit prior to four years old in infants evaluated for micrognathia.
Study design: Single-center retrospective analysis of 218 patients admitted and evaluated with congenital micrognathia during infancy. Outcomes were compared based on treatment (medical, mandibular distraction osteogenesis, or tracheostomy), and also compared based on syndromic status.
Results: Tube feeding was required by 81% of infants at discharge and 41% at follow-up. Respiratory support was required by 32% at discharge and 22% at follow-up. There were no differences in feeding and respiratory support at discharge and at follow-up between medical treatment and mandibular distraction osteogenesis. Tracheostomy was associated with more tube feeding and respiratory support at both discharge and at follow-up. Genetic syndromes were more likely to require tube feeding and respiratory support.
Conclusion: Long-term feeding and respiratory support are common in infants hospitalized with micrognathia.
期刊介绍:
The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development.
The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.