n-3 PUFAs二十二碳六烯酸和二十碳五烯酸是局部皮肤应用的有效天然促分解成分。

IF 2.7 4区医学 Q2 DERMATOLOGY

International Journal of Cosmetic Science Pub Date : 2025-04-24 DOI:10.1111/ics.13068

John Nip, Kevin Hermanson, Jian-Ming Lee

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引用次数: 0

摘要

皮肤遇到许多挑战，导致炎症反应。要使皮肤恢复健康状态，必须解决这种炎症。综述了外用n-3 PUFAs，特别是DHA和EPA在解决皮肤炎症和促进皮肤健康方面的作用。回顾文献和联合利华的数据，DHA/EPA对皮肤有益。PubMed/MEDLINE，谷歌搜索外部文献以及联合利华的数据有关皮肤炎症，促缓解，以及DHA和EPA的作用。总结了DHA和EPA在提供皮肤炎症的促解决方面的证据。DHA和EPA及其衍生的特殊促溶解介质（SPMs）可以减轻各种应激源引起的皮肤炎症反应，维持皮肤健康。

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n-3 PUFAs docosahexaenoic acid and eicosapentaenoic acid are effective natural pro-resolution ingredients for topical skin applications.

Skin encounters many challenges that lead to an inflammatory response. Resolution of this inflammation is needed to return the skin to a healthy state. A review of the role of topical n-3 PUFAs, particularly DHA and EPA, in resolving skin inflammation and promoting skin health is presented. A review of the literature and Unilever data on DHA/EPA pro-resolution skin benefits. PubMed/MEDLINE, Google search of external literature as well as Unilever data relating to skin inflammation, pro-resolution, and the role of DHA and EPA. Evidence of DHA and EPA in providing pro-resolution of skin inflammation are summarized. DHA and EPA, and their derived specialized pro-resolving mediators (SPMs), can attenuate the skin inflammatory response induced by various stressors and maintain skin health.

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来源期刊

International Journal of Cosmetic Science DERMATOLOGY-

CiteScore

4.60

自引率

4.30%

发文量

期刊介绍： The Journal publishes original refereed papers, review papers and correspondence in the fields of cosmetic research. It is read by practising cosmetic scientists and dermatologists, as well as specialists in more diverse disciplines that are developing new products which contact the skin, hair, nails or mucous membranes. The aim of the Journal is to present current scientific research, both pure and applied, in: cosmetics, toiletries, perfumery and allied fields. Areas that are of particular interest include: studies in skin physiology and interactions with cosmetic ingredients, innovation in claim substantiation methods (in silico, in vitro, ex vivo, in vivo), human and in vitro safety testing of cosmetic ingredients and products, physical chemistry and technology of emulsion and dispersed systems, theory and application of surfactants, new developments in olfactive research, aerosol technology and selected aspects of analytical chemistry.