Esraa A. Makhdom, Alisha Maher, Ryan Ottridge, Mathew Nicholls, Asad Ali, Brendan G. Cooper, Ramzi A. Ajjan, Srikanth Bellary, Wasim Hanif, Fahmy Hanna, David Hughes, Vijay Jayagopal, Rajni Mahto, Mayank Patel, James Young, Ananth U. Nayak, Mimi Z. Chen, Julie Kyaw-Tun, Susana Gonzalez, Ravikanth Gouni, Anuradhaa Subramanian, Nicola J. Adderley, Abd A. Tahrani
{"title":"2型糖尿病患者睡眠时间与肥胖之间的关系：一项纵向研究。","authors":"Esraa A. Makhdom, Alisha Maher, Ryan Ottridge, Mathew Nicholls, Asad Ali, Brendan G. Cooper, Ramzi A. Ajjan, Srikanth Bellary, Wasim Hanif, Fahmy Hanna, David Hughes, Vijay Jayagopal, Rajni Mahto, Mayank Patel, James Young, Ananth U. Nayak, Mimi Z. Chen, Julie Kyaw-Tun, Susana Gonzalez, Ravikanth Gouni, Anuradhaa Subramanian, Nicola J. Adderley, Abd A. Tahrani","doi":"10.1111/dme.70051","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Obesity is prevalent in patients with type 2 diabetes (T2D) and negatively impacts diabetes outcomes. While studies in the general population have established a link between sleep duration and obesity, this relationship in T2D remains unclear.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To assess the association between sleep duration and adiposity in patients with T2D.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This prospective study of adults enrolled in the SLEEP T2D study from 13 UK NHS Trusts. Sleep duration was self-reported using the Pittsburgh Sleep Quality Index (PSQI) and categorized as short (≤ 6 h/ night), long (> 9 h/night) or (normal > 6-9 h/night). Adiposity was assessed using body mass index (BMI) and waist circumference.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Among 229 patients (61% male, mean age 61.2 (<span></span><math>\n <semantics>\n <mrow>\n <mo>±</mo>\n </mrow>\n </semantics></math>11.7) years, 63.7% with BMI ≥ 30 kg/m<sup>2</sup>). At baseline, sleep duration negatively correlated with BMI (<i>r</i> = −0.27, <i>p</i> < 0.001) and waist circumference (<i>r</i> = −0.25, <i>p</i> = 0.001). After adjusting for potential confounders in different models, short sleep duration was associated with higher BMI (β = −1.01; <i>p</i> = 0.006) and waist circumference (β = −1.91; <i>p</i> = 0.01). Following a median follow-up of 26.5 months, short sleep at baseline was associated with a 5% or more gain in BMI (adjusted OR 10.03; 95% CI 1.55–64.84; <i>p</i> = 0.01).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Short sleep duration is associated with higher adiposity measures (BMI and waist circumference) and weight gain in patients with T2D. Addressing sleep duration may reduce the burden of obesity in T2D, and future studies in this area are warranted.</p>\n </section>\n </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"42 6","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70051","citationCount":"0","resultStr":"{\"title\":\"Association between sleep duration and obesity in patients with type 2 diabetes: A longitudinal study\",\"authors\":\"Esraa A. Makhdom, Alisha Maher, Ryan Ottridge, Mathew Nicholls, Asad Ali, Brendan G. Cooper, Ramzi A. Ajjan, Srikanth Bellary, Wasim Hanif, Fahmy Hanna, David Hughes, Vijay Jayagopal, Rajni Mahto, Mayank Patel, James Young, Ananth U. Nayak, Mimi Z. Chen, Julie Kyaw-Tun, Susana Gonzalez, Ravikanth Gouni, Anuradhaa Subramanian, Nicola J. Adderley, Abd A. Tahrani\",\"doi\":\"10.1111/dme.70051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Obesity is prevalent in patients with type 2 diabetes (T2D) and negatively impacts diabetes outcomes. While studies in the general population have established a link between sleep duration and obesity, this relationship in T2D remains unclear.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To assess the association between sleep duration and adiposity in patients with T2D.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>This prospective study of adults enrolled in the SLEEP T2D study from 13 UK NHS Trusts. Sleep duration was self-reported using the Pittsburgh Sleep Quality Index (PSQI) and categorized as short (≤ 6 h/ night), long (> 9 h/night) or (normal > 6-9 h/night). Adiposity was assessed using body mass index (BMI) and waist circumference.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Among 229 patients (61% male, mean age 61.2 (<span></span><math>\\n <semantics>\\n <mrow>\\n <mo>±</mo>\\n </mrow>\\n </semantics></math>11.7) years, 63.7% with BMI ≥ 30 kg/m<sup>2</sup>). At baseline, sleep duration negatively correlated with BMI (<i>r</i> = −0.27, <i>p</i> < 0.001) and waist circumference (<i>r</i> = −0.25, <i>p</i> = 0.001). After adjusting for potential confounders in different models, short sleep duration was associated with higher BMI (β = −1.01; <i>p</i> = 0.006) and waist circumference (β = −1.91; <i>p</i> = 0.01). Following a median follow-up of 26.5 months, short sleep at baseline was associated with a 5% or more gain in BMI (adjusted OR 10.03; 95% CI 1.55–64.84; <i>p</i> = 0.01).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Short sleep duration is associated with higher adiposity measures (BMI and waist circumference) and weight gain in patients with T2D. Addressing sleep duration may reduce the burden of obesity in T2D, and future studies in this area are warranted.</p>\\n </section>\\n </div>\",\"PeriodicalId\":11251,\"journal\":{\"name\":\"Diabetic Medicine\",\"volume\":\"42 6\",\"pages\":\"\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70051\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diabetic Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/dme.70051\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetic Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/dme.70051","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
摘要
背景：肥胖在2型糖尿病（T2D）患者中普遍存在，并对糖尿病预后产生负面影响。虽然对普通人群的研究已经建立了睡眠时间和肥胖之间的联系，但这种关系在糖尿病中仍不清楚。目的：评估t2dm患者睡眠时间与肥胖之间的关系。方法：这项前瞻性研究纳入了13个英国NHS信托基金的睡眠T2D研究的成年人。使用匹兹堡睡眠质量指数（PSQI）自我报告睡眠时间，并将其分为短（≤6小时/晚）、长（> 9小时/晚）或（正常> 6-9小时/晚）。用体重指数（BMI）和腰围来评估肥胖。结果：229例患者中(61例% male, mean age 61.2 ( ± $$ \pm $$ 11.7) years, 63.7% with BMI ≥ 30 kg/m2). At baseline, sleep duration negatively correlated with BMI (r = -0.27, p Conclusion: Short sleep duration is associated with higher adiposity measures (BMI and waist circumference) and weight gain in patients with T2D. Addressing sleep duration may reduce the burden of obesity in T2D, and future studies in this area are warranted.
Association between sleep duration and obesity in patients with type 2 diabetes: A longitudinal study
Background
Obesity is prevalent in patients with type 2 diabetes (T2D) and negatively impacts diabetes outcomes. While studies in the general population have established a link between sleep duration and obesity, this relationship in T2D remains unclear.
Objectives
To assess the association between sleep duration and adiposity in patients with T2D.
Methods
This prospective study of adults enrolled in the SLEEP T2D study from 13 UK NHS Trusts. Sleep duration was self-reported using the Pittsburgh Sleep Quality Index (PSQI) and categorized as short (≤ 6 h/ night), long (> 9 h/night) or (normal > 6-9 h/night). Adiposity was assessed using body mass index (BMI) and waist circumference.
Results
Among 229 patients (61% male, mean age 61.2 (11.7) years, 63.7% with BMI ≥ 30 kg/m2). At baseline, sleep duration negatively correlated with BMI (r = −0.27, p < 0.001) and waist circumference (r = −0.25, p = 0.001). After adjusting for potential confounders in different models, short sleep duration was associated with higher BMI (β = −1.01; p = 0.006) and waist circumference (β = −1.91; p = 0.01). Following a median follow-up of 26.5 months, short sleep at baseline was associated with a 5% or more gain in BMI (adjusted OR 10.03; 95% CI 1.55–64.84; p = 0.01).
Conclusion
Short sleep duration is associated with higher adiposity measures (BMI and waist circumference) and weight gain in patients with T2D. Addressing sleep duration may reduce the burden of obesity in T2D, and future studies in this area are warranted.
期刊介绍：
Diabetic Medicine, the official journal of Diabetes UK, is published monthly simultaneously, in print and online editions.
The journal publishes a range of key information on all clinical aspects of diabetes mellitus, ranging from human genetic studies through clinical physiology and trials to diabetes epidemiology. We do not publish original animal or cell culture studies unless they are part of a study of clinical diabetes involving humans. Categories of publication include research articles, reviews, editorials, commentaries, and correspondence. All material is peer-reviewed.
We aim to disseminate knowledge about diabetes research with the goal of improving the management of people with diabetes. The journal therefore seeks to provide a forum for the exchange of ideas between clinicians and researchers worldwide. Topics covered are of importance to all healthcare professionals working with people with diabetes, whether in primary care or specialist services.
Surplus generated from the sale of Diabetic Medicine is used by Diabetes UK to know diabetes better and fight diabetes more effectively on behalf of all people affected by and at risk of diabetes as well as their families and carers.”
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
