[减肥代谢手术2025]。

Innere Medizin (Heidelberg, Germany) Pub Date : 2025-05-01 Epub Date: 2025-04-28 DOI:10.1007/s00108-025-01901-9
Thomas P Hüttl, Peter Stauch
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引用次数: 0

摘要

外科手术是病态肥胖及其相关并发症跨学科治疗的重要组成部分。目标不仅仅是控制体重(减肥手术),还包括控制整个新陈代谢。减肥/代谢手术不仅是目前治疗2型糖尿病(DMT2)尤其是肥胖患者最有效的方式,而且已被证明是治疗许多其他肥胖相关继发性疾病的关键工具。除了主要的作用方式,即限制和吸收不良,许多其他机制也是研究的主题,因为代谢影响尤其发生在术后早期,也可以在非肥胖个体中得到证明。今天,各种各样的外科手术可以帮助解决病人的具体问题。例如,套筒胃切除术、Roux-en - Y胃旁路术、omega环旁路术、单吻合术十二指肠回肠旁路术(SADI)、单吻合术套筒回肠旁路术(SASI)、十二指肠开关胆胰分流术(BPD-DS)、胃带以及纯内镜手术,如胃内球囊或内镜套筒胃成形术(ESG)。长期的、有组织的、最好是多学科的后续护理对于取得积极的长期结果至关重要,应包括:营养治疗、实验室检查、调整药物治疗、鼓励参加癌症筛查,以及对神经症状和诸如体重恢复、抑郁复发或成瘾问题等关键治疗情况保持警惕。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Bariatric metabolic surgery 2025].

Surgical procedures form an integral part of the interdisciplinary treatment of morbid obesity and its associated complications. The objective goes beyond mere weight control (bariatric surgery) and includes controlling the entire metabolism. Bariatric/metabolic procedures have not only become the currently most effective form of treatment for diabetes mellitus type 2 (DMT2) particularly in obese patients, but it has also proven to be a key tool for many other obesity-related secondary diseases. In addition to the main modes of action, i.e., restriction and malabsorption, numerous other mechanisms are the subject of research, since the metabolic effects in particular occur in the early postoperative period and can also be demonstrated in non-obese individuals. Today, a variety of surgical procedures are available to help address patient-specific issues. Examples include sleeve gastrectomy, Roux-en‑Y gastric bypass, omega loop bypass, single anastomosis duodeno-ileal bypass (SADI) surgery, single anastomosis sleeve-ileal bypass (SASI) surgery, biliopancreatic diversion with duodenal switch (BPD-DS), gastric band, and purely endoscopic procedures such as intragastric balloon or endoscopic sleeve gastroplasty (ESG). Long-term, structured, and preferably multidisciplinary follow-up care is essential for a positive long-term outcome and should include: nutritional therapy, laboratory tests, adjustment of pharmacotherapy, encouragement to take part in cancer screening, as well as vigilance regarding neurological symptoms and critical treatment situations such as weight regain, recurrence of depression or addiction problems.

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