家猫肝炎病毒，一种与猫肝脏疾病相关的乙型肝炎样病毒。

IF 1.9 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Clinics of North America-Small Animal Practice Pub Date : 2025-05-12 DOI:10.1016/j.cvsm.2025.03.006

Julia A Beatty, Thomas Tu, John M Cullen

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引用次数: 0

摘要

2018年，报道了一个令人惊讶的发现；猫会自然感染一种与乙型肝炎病毒（HBV）有关的病毒，即家猫肝炎病毒（DCH）。HBV在人类中引起慢性肝炎和肝细胞癌，HBV样病毒在啮齿动物中引起类似疾病。如果DCH对猫的健康产生负面影响，那么对诊断、治疗和疫苗接种的需求就会随之而来。因此，了解猫DCH的致病潜力以及任何相关疾病负担的大小是关键目标。在此，我们通过回顾已发表的关于DCH的研究，结合我们对HBV和HBV样病毒的了解，来评估这些目标的进展。

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Domestic Cat Hepadnavirus, a Hepatitis B-like Virus Associated with Feline Liver Disease.

In 2018, a surprising finding was reported; cats are naturally infected with a virus related to hepatitis B virus (HBV), domestic cat hepadnavirus (DCH). HBV causes chronic hepatitis and hepatocellular carcinoma in people, and HBV-like viruses cause similar diseases in rodents. If DCH negatively impacts feline health then demand for diagnostics, therapeutics, and vaccination will follow. Hence, understanding pathogenic potential of DCH for cats, and the size of any associated disease burden are critical goals. Here we evaluate progress made towards these goals by reviewing published studies of DCH against the backdrop of our understanding of HBV and HBV-like viruses.

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来源期刊

Veterinary Clinics of North America-Small Animal Practice 农林科学-兽医学

CiteScore

3.80

自引率

0.00%

发文量

123

审稿时长

18-36 weeks

期刊介绍： Veterinary Clinics of North America: Small Animal Practice offers you the most current information on the treatment of small animals such as cats and dogs, updates you on the latest advances, and provides a sound basis for choosing treatment options. Published bi-monthly—in January, March, May, July, September, November—each issue focuses on a single topic in small animal practice, including endocrinology, fluids and electrolytes, gastroenterology, infectious diseases, neurology, oncology, urology, respiratory issues , surgical information, small animal behavior, laboratory medicine, imaging methods, and nutrition.