{"title":"山药对断奶仔猪生长性能、生化指标、免疫及肠道健康的影响","authors":"Xiang-Yi Pan, Zheng-Ying Qiu, Chen Liu, Chuan Wang, Xiaowu Wang, Li-Na Huang, Si-Fan Li, Xiong-Wei Shi, Shao-Guang Ge, Rui-Hua Xin","doi":"10.3389/fvets.2025.1529881","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Weaning stress syndrome in piglets seriously endangers the healthy development of the breeding industry. <i>Dioscorea oppositifolia</i> L. (Chinese yam, YAM) has activities such as boosting immunity and regulating gastrointestinal function. In order to explore the potential efficacy of YAM on weaned piglets, this study aimed to investigate the effects of growth performance, immune function, intestinal health and intestinal flora composition of weaned piglets.</p><p><strong>Methods: </strong>Forty-eight 28-day-old weaned piglets were randomly divided into a control group, YAML group and YAMH group, with 0, 1 and 2% YAM added to the basal diet, respectively. During the experiment, the piglets' feed intake was recorded, and blood and fecal samples were collected. After the feeding period, intestinal tissue samples and colon content samples were collected for testing.</p><p><strong>Results: </strong>The results showed that adding YAM to the diet can lower the incidence of diarrhea in weaned piglets, improve growth performance and nutrient digestibility, and reduce serum enzyme activity alanine aminotransferase (ALT), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C); in addition, YAM can also increase serum immunoglobulins (Ig) and antibody titers, regulate the level of inflammatory factors, and promote the expression of secretory immunoglobulin A (SIgA) protein in the intestine. Furthermore, supplementation with YAM can increase the villus height (VH), the ratio of villus height to crypt depth (V/C), and the expression of Tight junctions (TJs), and also has a positive regulatory effect on the intestinal flora.</p><p><strong>Discussion: </strong>In summary, YAM alleviates weaning stress syndrome in piglets by promoting growth performance, improving immune function and disease resistance, improving intestinal morphology and mucosal immunity, and regulating the intestinal microbial composition of piglets. This provides a theoretical basis for the development and application of YAM as a new plant-derived feed additive.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1529881"},"PeriodicalIF":2.6000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063354/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effects of <i>Dioscorea oppositifolia</i> L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets.\",\"authors\":\"Xiang-Yi Pan, Zheng-Ying Qiu, Chen Liu, Chuan Wang, Xiaowu Wang, Li-Na Huang, Si-Fan Li, Xiong-Wei Shi, Shao-Guang Ge, Rui-Hua Xin\",\"doi\":\"10.3389/fvets.2025.1529881\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Weaning stress syndrome in piglets seriously endangers the healthy development of the breeding industry. <i>Dioscorea oppositifolia</i> L. (Chinese yam, YAM) has activities such as boosting immunity and regulating gastrointestinal function. In order to explore the potential efficacy of YAM on weaned piglets, this study aimed to investigate the effects of growth performance, immune function, intestinal health and intestinal flora composition of weaned piglets.</p><p><strong>Methods: </strong>Forty-eight 28-day-old weaned piglets were randomly divided into a control group, YAML group and YAMH group, with 0, 1 and 2% YAM added to the basal diet, respectively. During the experiment, the piglets' feed intake was recorded, and blood and fecal samples were collected. After the feeding period, intestinal tissue samples and colon content samples were collected for testing.</p><p><strong>Results: </strong>The results showed that adding YAM to the diet can lower the incidence of diarrhea in weaned piglets, improve growth performance and nutrient digestibility, and reduce serum enzyme activity alanine aminotransferase (ALT), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C); in addition, YAM can also increase serum immunoglobulins (Ig) and antibody titers, regulate the level of inflammatory factors, and promote the expression of secretory immunoglobulin A (SIgA) protein in the intestine. Furthermore, supplementation with YAM can increase the villus height (VH), the ratio of villus height to crypt depth (V/C), and the expression of Tight junctions (TJs), and also has a positive regulatory effect on the intestinal flora.</p><p><strong>Discussion: </strong>In summary, YAM alleviates weaning stress syndrome in piglets by promoting growth performance, improving immune function and disease resistance, improving intestinal morphology and mucosal immunity, and regulating the intestinal microbial composition of piglets. This provides a theoretical basis for the development and application of YAM as a new plant-derived feed additive.</p>\",\"PeriodicalId\":12772,\"journal\":{\"name\":\"Frontiers in Veterinary Science\",\"volume\":\"12 \",\"pages\":\"1529881\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063354/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Veterinary Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.3389/fvets.2025.1529881\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Veterinary Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fvets.2025.1529881","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Effects of Dioscorea oppositifolia L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets.
Introduction: Weaning stress syndrome in piglets seriously endangers the healthy development of the breeding industry. Dioscorea oppositifolia L. (Chinese yam, YAM) has activities such as boosting immunity and regulating gastrointestinal function. In order to explore the potential efficacy of YAM on weaned piglets, this study aimed to investigate the effects of growth performance, immune function, intestinal health and intestinal flora composition of weaned piglets.
Methods: Forty-eight 28-day-old weaned piglets were randomly divided into a control group, YAML group and YAMH group, with 0, 1 and 2% YAM added to the basal diet, respectively. During the experiment, the piglets' feed intake was recorded, and blood and fecal samples were collected. After the feeding period, intestinal tissue samples and colon content samples were collected for testing.
Results: The results showed that adding YAM to the diet can lower the incidence of diarrhea in weaned piglets, improve growth performance and nutrient digestibility, and reduce serum enzyme activity alanine aminotransferase (ALT), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C); in addition, YAM can also increase serum immunoglobulins (Ig) and antibody titers, regulate the level of inflammatory factors, and promote the expression of secretory immunoglobulin A (SIgA) protein in the intestine. Furthermore, supplementation with YAM can increase the villus height (VH), the ratio of villus height to crypt depth (V/C), and the expression of Tight junctions (TJs), and also has a positive regulatory effect on the intestinal flora.
Discussion: In summary, YAM alleviates weaning stress syndrome in piglets by promoting growth performance, improving immune function and disease resistance, improving intestinal morphology and mucosal immunity, and regulating the intestinal microbial composition of piglets. This provides a theoretical basis for the development and application of YAM as a new plant-derived feed additive.
期刊介绍：
Frontiers in Veterinary Science is a global, peer-reviewed, Open Access journal that bridges animal and human health, brings a comparative approach to medical and surgical challenges, and advances innovative biotechnology and therapy.
Veterinary research today is interdisciplinary, collaborative, and socially relevant, transforming how we understand and investigate animal health and disease. Fundamental research in emerging infectious diseases, predictive genomics, stem cell therapy, and translational modelling is grounded within the integrative social context of public and environmental health, wildlife conservation, novel biomarkers, societal well-being, and cutting-edge clinical practice and specialization. Frontiers in Veterinary Science brings a 21st-century approach—networked, collaborative, and Open Access—to communicate this progress and innovation to both the specialist and to the wider audience of readers in the field.
Frontiers in Veterinary Science publishes articles on outstanding discoveries across a wide spectrum of translational, foundational, and clinical research. The journal''s mission is to bring all relevant veterinary sciences together on a single platform with the goal of improving animal and human health.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
