山药对断奶仔猪生长性能、生化指标、免疫及肠道健康的影响

IF 2.6 2区 农林科学 Q1 VETERINARY SCIENCES
Frontiers in Veterinary Science Pub Date : 2025-04-25 eCollection Date: 2025-01-01 DOI:10.3389/fvets.2025.1529881
Xiang-Yi Pan, Zheng-Ying Qiu, Chen Liu, Chuan Wang, Xiaowu Wang, Li-Na Huang, Si-Fan Li, Xiong-Wei Shi, Shao-Guang Ge, Rui-Hua Xin
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引用次数: 0

摘要

仔猪断奶应激综合征严重危害养殖业的健康发展。薯蓣(Dioscorea opposite folia L.)具有增强免疫、调节胃肠功能等活性。为了探讨甘薯对断奶仔猪的潜在功效,本试验旨在研究甘薯对断奶仔猪生长性能、免疫功能、肠道健康和肠道菌群组成的影响。方法:48头28日龄断奶仔猪随机分为对照组、YAML组和YAMH组,分别在基础饲粮中添加0、1%和2%的YAM。试验期间记录仔猪采食量,采集血液和粪便样本。饲喂期结束后,采集肠道组织标本和结肠内容物标本进行检测。结果:结果表明,饲粮中添加甘薯可降低断奶仔猪腹泻发生率,提高生长性能和营养物质消化率,降低血清谷丙转氨酶(ALT)活性、总胆固醇(TC)和低密度脂蛋白胆固醇(LDL-C);此外,YAM还能提高血清免疫球蛋白(Ig)和抗体滴度,调节炎症因子水平,促进肠道分泌性免疫球蛋白A (SIgA)蛋白的表达。此外,添加YAM可以增加绒毛高度(VH)、绒毛高度/隐窝深度(V/C)和紧密连接(TJs)的表达,并对肠道菌群具有积极的调节作用。综上所述,YAM可通过促进仔猪生长性能、提高免疫功能和抗病能力、改善肠道形态和黏膜免疫、调节仔猪肠道微生物组成等方式缓解仔猪断奶应激综合征。这为甘薯作为一种新型植物源性饲料添加剂的开发和应用提供了理论依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Dioscorea oppositifolia L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets.

Introduction: Weaning stress syndrome in piglets seriously endangers the healthy development of the breeding industry. Dioscorea oppositifolia L. (Chinese yam, YAM) has activities such as boosting immunity and regulating gastrointestinal function. In order to explore the potential efficacy of YAM on weaned piglets, this study aimed to investigate the effects of growth performance, immune function, intestinal health and intestinal flora composition of weaned piglets.

Methods: Forty-eight 28-day-old weaned piglets were randomly divided into a control group, YAML group and YAMH group, with 0, 1 and 2% YAM added to the basal diet, respectively. During the experiment, the piglets' feed intake was recorded, and blood and fecal samples were collected. After the feeding period, intestinal tissue samples and colon content samples were collected for testing.

Results: The results showed that adding YAM to the diet can lower the incidence of diarrhea in weaned piglets, improve growth performance and nutrient digestibility, and reduce serum enzyme activity alanine aminotransferase (ALT), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C); in addition, YAM can also increase serum immunoglobulins (Ig) and antibody titers, regulate the level of inflammatory factors, and promote the expression of secretory immunoglobulin A (SIgA) protein in the intestine. Furthermore, supplementation with YAM can increase the villus height (VH), the ratio of villus height to crypt depth (V/C), and the expression of Tight junctions (TJs), and also has a positive regulatory effect on the intestinal flora.

Discussion: In summary, YAM alleviates weaning stress syndrome in piglets by promoting growth performance, improving immune function and disease resistance, improving intestinal morphology and mucosal immunity, and regulating the intestinal microbial composition of piglets. This provides a theoretical basis for the development and application of YAM as a new plant-derived feed additive.

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来源期刊
Frontiers in Veterinary Science
Frontiers in Veterinary Science Veterinary-General Veterinary
CiteScore
4.80
自引率
9.40%
发文量
1870
审稿时长
14 weeks
期刊介绍: Frontiers in Veterinary Science is a global, peer-reviewed, Open Access journal that bridges animal and human health, brings a comparative approach to medical and surgical challenges, and advances innovative biotechnology and therapy. Veterinary research today is interdisciplinary, collaborative, and socially relevant, transforming how we understand and investigate animal health and disease. Fundamental research in emerging infectious diseases, predictive genomics, stem cell therapy, and translational modelling is grounded within the integrative social context of public and environmental health, wildlife conservation, novel biomarkers, societal well-being, and cutting-edge clinical practice and specialization. Frontiers in Veterinary Science brings a 21st-century approach—networked, collaborative, and Open Access—to communicate this progress and innovation to both the specialist and to the wider audience of readers in the field. Frontiers in Veterinary Science publishes articles on outstanding discoveries across a wide spectrum of translational, foundational, and clinical research. The journal''s mission is to bring all relevant veterinary sciences together on a single platform with the goal of improving animal and human health.
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