致死性全身毛细血管渗漏综合征患者心肌小血管超微结构的观察。

IF 1.2 4区 医学 Q3 PATHOLOGY
Hiroaki Kawano, Koichi Kawamura, Koji Maemura, Shinji Okano
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引用次数: 0

摘要

一名29岁日本女性因发热、心源性休克和心脏骤停入院,入院18小时后死亡。患者被诊断为与2019冠状病毒病相关的全身毛细血管渗漏综合征。电镜检查显示右心室心肌间质有广泛的血细胞和血浆渗漏,毛细血管受损,网状血管引流至底比斯静脉。这些结果表明,严重的毛细血管泄漏和由于毛细血管损伤引起的管腔阻塞是全身性毛细血管泄漏综合征的主要特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ultrastructure of the small vessels in the myocardium in a patient with fatal systemic capillary leak syndrome.

A 29-year-old Japanese woman was admitted to our hospital with fever, cardiogenic shock, and cardiac arrest and died 18 h after admission. The patient was diagnosed with systemic capillary leak syndrome associated with coronavirus disease 2019. Electron microscopy of the biopsied right-ventricular myocardium revealed extensive interstitial leakage of blood cells and plasma, damaged capillaries, and reticular vessel drainage into the Thebesian vein. These findings indicate that severe capillary leak and lumen occlusion due to damaged capillaries are the main features of systemic capillary leak syndrome.

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来源期刊
Medical Molecular Morphology
Medical Molecular Morphology 医学-病理学
CiteScore
2.90
自引率
5.60%
发文量
30
审稿时长
>12 weeks
期刊介绍: Medical Molecular Morphology is an international forum for researchers in both basic and clinical medicine to present and discuss new research on the structural mechanisms and the processes of health and disease at the molecular level. The structures of molecules, organelles, cells, tissues, and organs determine their normal function. Disease is thus best understood in terms of structural changes in these different levels of biological organization, especially in molecules and molecular interactions as well as the cellular localization of chemical components. Medical Molecular Morphology welcomes articles on basic or clinical research in the fields of cell biology, molecular biology, and medical, veterinary, and dental sciences using techniques for structural research such as electron microscopy, confocal laser scanning microscopy, enzyme histochemistry, immunohistochemistry, radioautography, X-ray microanalysis, and in situ hybridization. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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