Catalina Grisolia, Gabriela Muñoz, Rodrigo Salgado, Cristian Herrera, Victor Neira, André V. Rubio
{"title":"智利中部鼠型啮齿动物SARS-CoV-2分子和血清学调查","authors":"Catalina Grisolia, Gabriela Muñoz, Rodrigo Salgado, Cristian Herrera, Victor Neira, André V. Rubio","doi":"10.1111/zph.13222","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>The potential role of rodents as reservoirs for SARS-CoV-2 has gained global attention due to their proximity to humans and their involvement in zoonotic disease transmission. Rodents were sampled from urban, rural and natural areas across the Metropolitan Region of Chile between June 2023 and June 2024. Molecular testing (RT-qPCR) revealed no active infections among the 421 analysed individuals, while serological assays (ELISA) detected SARS-CoV-2 antibodies in 4 of 459 rodents (0.87%). All seropositive rodents were <i>Rattus rattus</i> captured in rural areas. These findings suggest localised exposure to SARS-CoV-2, possibly influenced by environmental or anthropogenic factors. The results align with global studies reporting sporadic rodent exposure to SARS-CoV-2, emphasising the importance of integrating molecular and serological approaches in zoonotic surveillance. Despite the low prevalence observed, the potential role of rodents in viral spillover and recombination events with other coronaviruses underscores the need for continued monitoring. These results contribute to understanding zoonotic dynamics and inform public health strategies in a One Health framework.</p>\n </div>","PeriodicalId":24025,"journal":{"name":"Zoonoses and Public Health","volume":"72 5","pages":"478-484"},"PeriodicalIF":2.3000,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Molecular and Serological Survey of SARS-CoV-2 in Murid Rodents From Central Chile\",\"authors\":\"Catalina Grisolia, Gabriela Muñoz, Rodrigo Salgado, Cristian Herrera, Victor Neira, André V. Rubio\",\"doi\":\"10.1111/zph.13222\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>The potential role of rodents as reservoirs for SARS-CoV-2 has gained global attention due to their proximity to humans and their involvement in zoonotic disease transmission. Rodents were sampled from urban, rural and natural areas across the Metropolitan Region of Chile between June 2023 and June 2024. Molecular testing (RT-qPCR) revealed no active infections among the 421 analysed individuals, while serological assays (ELISA) detected SARS-CoV-2 antibodies in 4 of 459 rodents (0.87%). All seropositive rodents were <i>Rattus rattus</i> captured in rural areas. These findings suggest localised exposure to SARS-CoV-2, possibly influenced by environmental or anthropogenic factors. The results align with global studies reporting sporadic rodent exposure to SARS-CoV-2, emphasising the importance of integrating molecular and serological approaches in zoonotic surveillance. Despite the low prevalence observed, the potential role of rodents in viral spillover and recombination events with other coronaviruses underscores the need for continued monitoring. These results contribute to understanding zoonotic dynamics and inform public health strategies in a One Health framework.</p>\\n </div>\",\"PeriodicalId\":24025,\"journal\":{\"name\":\"Zoonoses and Public Health\",\"volume\":\"72 5\",\"pages\":\"478-484\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-04-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zoonoses and Public Health\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/zph.13222\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zoonoses and Public Health","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/zph.13222","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Molecular and Serological Survey of SARS-CoV-2 in Murid Rodents From Central Chile
The potential role of rodents as reservoirs for SARS-CoV-2 has gained global attention due to their proximity to humans and their involvement in zoonotic disease transmission. Rodents were sampled from urban, rural and natural areas across the Metropolitan Region of Chile between June 2023 and June 2024. Molecular testing (RT-qPCR) revealed no active infections among the 421 analysed individuals, while serological assays (ELISA) detected SARS-CoV-2 antibodies in 4 of 459 rodents (0.87%). All seropositive rodents were Rattus rattus captured in rural areas. These findings suggest localised exposure to SARS-CoV-2, possibly influenced by environmental or anthropogenic factors. The results align with global studies reporting sporadic rodent exposure to SARS-CoV-2, emphasising the importance of integrating molecular and serological approaches in zoonotic surveillance. Despite the low prevalence observed, the potential role of rodents in viral spillover and recombination events with other coronaviruses underscores the need for continued monitoring. These results contribute to understanding zoonotic dynamics and inform public health strategies in a One Health framework.
期刊介绍：
Zoonoses and Public Health brings together veterinary and human health researchers and policy-makers by providing a venue for publishing integrated and global approaches to zoonoses and public health. The Editors will consider papers that focus on timely collaborative and multi-disciplinary research in zoonoses and public health. This journal provides rapid publication of original papers, reviews, and potential discussion papers embracing this collaborative spirit. Papers should advance the scientific knowledge of the sources, transmission, prevention and control of zoonoses and be authored by scientists with expertise in areas such as microbiology, virology, parasitology and epidemiology. Articles that incorporate recent data into new methods, applications, or approaches (e.g. statistical modeling) which enhance public health are strongly encouraged.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
