用分子包封法提高水溶液中红色荧光团的亮度。

IF 1.1 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Chimia Pub Date : 2025-04-30 DOI:10.2533/chimia.2025.259

Liza Briant, Alexandre Fürstenberg

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引用次数: 0

摘要

生物分子环境中的荧光光谱和显微镜通常在水溶液中进行，最好使用发红染料。然而，水会熄灭它们的荧光。我们在这篇文章中探讨了红色荧光团和大环（如环糊精和葫芦酚）之间的主客体相互作用如何通过屏蔽染料免受水的影响来防止猝灭，从而提高它们的亮度。我们成功地将该策略应用于超分辨率成像。

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Enhancing the Brightness of Red-emitting Fluorophores in Aqueous Solution by Molecular Encapsulation.

Fluorescence spectroscopy and microscopy in biomolecular environments are usually performed in aqueous solution and preferably using red-emitting dyes. However, water quenches their fluorescence. We explore in this contribution how host-guest interactions between red-emitting fluorophores and macrocycles such as cyclodextrins and cucurbiturils can prevent quenching by shielding the dyes from water, thereby enhancing their brightness. We successfully apply this strategy in super-resolution imaging.

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来源期刊

Chimia 化学-化学综合

CiteScore

1.60

自引率

0.00%

发文量

144

审稿时长

2 months

期刊介绍： CHIMIA, a scientific journal for chemistry in the broadest sense covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.