多发和/或严重损伤患者泌尿生殖道损伤的初始手术治疗:系统综述和临床实践指南更新

IF 2.2 3区 医学 Q2 EMERGENCY MEDICINE
Christian Ruf, Luis Kluth, Sarah Wahlen, Jessica Breuing, Tim Nestler
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引用次数: 0

摘要

目的:我们的目的是更新基于证据和共识的建议,针对多发创伤和/或严重损伤患者的泌尿生殖系统损伤的初始手术治疗。该指南主题是2022年更新的《德国多发性创伤和/或严重损伤患者治疗指南》的一部分。方法:系统检索MEDLINE和Embase至2021年6月。纳入随机对照试验、前瞻性队列研究和比较登记研究,如果它们比较了医院环境中泌尿生殖系统损伤的手术和/或治疗干预措施。我们考虑了与患者相关的临床结果,如死亡率和出血控制,或凝血参数作为替代结果。使用NICE 2012检查表评估偏倚风险。证据以叙述的方式综合,专家共识被用来制定建议并确定其力度。结果:确定了两项新的研究。所涵盖的主题是手术和非手术治疗后的结果比较,以及腹膜外膀胱损伤患者手术修复与导尿管引流的比较。修改了三项建议,其中一项是出于编辑原因。各方达成强烈共识。结论:提出以下主要建议。1. 肾动脉损伤可采用血管内入路治疗。2. 根据损伤的类型和严重程度以及伴随损伤,肾损伤的处理应以保存器官为目的。3. 腹膜外膀胱破裂不累及膀胱颈部应保守治疗导尿。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Initial surgical management of injuries to the urogenital tract in patients with polytrauma and/or severe injuries: a systematic review and clinical practice guideline update.

Purpose: Our aim was to update evidence-based and consensus-based recommendations for the initial surgical management of urogenital injuries in patients with polytrauma and/or severe injuries based on current evidence. This guideline topic is part of the 2022 update of the German Guideline on the Treatment of Patients with Polytrauma and/or Severe Injuries.

Methods: MEDLINE and Embase were systematically searched to June 2021. Randomised controlled trials, prospective cohort studies, and comparative registry studies were included if they compared surgical and/or therapeutic interventions for urogenital injuries in the hospital setting. We considered patient-relevant clinical outcomes such as mortality and bleeding control, or coagulation parameters as surrogate outcomes. Risk of bias was assessed using NICE 2012 checklists. The evidence was synthesised narratively, and expert consensus was used to develop recommendations and determine their strength.

Results: Two new studies were identified. The topics covered were the comparison of outcomes after surgical and nonsurgical management as well as the use of surgical repair versus catheter drainage in patients with extraperitoneal bladder injuries. Three recommendations were modified, one of which for editorial reasons. All achieved strong consensus.

Conclusion: The following key recommendations are made. 1. Renal artery injuries can be managed using an endovascular approach. 2. Depending on the type and severity of the injury and concomitant injuries, renal injuries should be managed with the intent to preserve the organ. 3. Extraperitoneal bladder ruptures without involvement of the bladder neck should be conservatively treated with catheterisation.

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来源期刊
CiteScore
4.50
自引率
14.30%
发文量
311
审稿时长
3 months
期刊介绍: The European Journal of Trauma and Emergency Surgery aims to open an interdisciplinary forum that allows for the scientific exchange between basic and clinical science related to pathophysiology, diagnostics and treatment of traumatized patients. The journal covers all aspects of clinical management, operative treatment and related research of traumatic injuries. Clinical and experimental papers on issues relevant for the improvement of trauma care are published. Reviews, original articles, short communications and letters allow the appropriate presentation of major and minor topics.
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