ER-to-lysosome-associated退化。

IF 8.1 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Current Biology Pub Date : 2025-05-05 DOI:10.1016/j.cub.2025.03.068

Maurizio Molinari

引用次数: 0

摘要

Maurizio Molinari介绍了内质网到溶酶体相关的降解-自噬和非自噬途径，将抗erd错误折叠的蛋白质传递到溶酶体进行降解，以维持细胞的蛋白质稳态。

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ER-to-lysosome-associated degradation.

Maurizio Molinari introduces ER-to-lysosome-associated degradation - the autophagic and non-autophagic pathways that deliver ERAD-resistant misfolded proteins to the lysosome for degradation to maintain cellular proteostasis.

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来源期刊

Current Biology 生物-生化与分子生物学

CiteScore

11.80

自引率

2.20%

发文量

869

审稿时长

46 days

期刊介绍： Current Biology is a comprehensive journal that showcases original research in various disciplines of biology. It provides a platform for scientists to disseminate their groundbreaking findings and promotes interdisciplinary communication. The journal publishes articles of general interest, encompassing diverse fields of biology. Moreover, it offers accessible editorial pieces that are specifically designed to enlighten non-specialist readers.