原发性肠系膜高分化炎性脂肪肉瘤伴粘膜延伸:一种高误诊风险的病变。

IF 0.6 Q4 SURGERY
Case Reports in Surgery Pub Date : 2025-04-19 eCollection Date: 2025-01-01 DOI:10.1155/cris/9162938
William Abel, Christopher J Peterson, David P Lebel, Douglas J Grider
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引用次数: 0

摘要

高分化脂肪肉瘤是常见的腹膜后病变,但当原发于小肠肠系膜时极为罕见,文献中只有少数病例报道。本文报告一例具有高误诊风险的肠系膜高分化炎性脂肪肉瘤伴粘膜延伸。广泛的鉴别诊断,仔细的组织病理学观察,辅助免疫组织化学研究,以及MDM2荧光原位杂交扩增是做出正确诊断的关键。如果这种病变首先在内窥镜粘膜活检的组织病理学上发现于固有层,则尤其如此。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary Mesenteric Well-Differentiated Inflammatory Liposarcoma With Mucosal Extension: A Lesion With High Risk for Misdiagnosis.

Well-differentiated liposarcomas are common retroperitoneal lesions, but exceedingly rare when primary to the small bowel mesentery, with only a handful of cases reported in the literature. Presented is a patient with a primary mesenteric well-differentiated inflammatory liposarcoma with mucosal extension at high risk for misdiagnosis. A broad differential diagnosis with careful histopathologic observation, ancillary immunohistochemical studies, and fluorescent in situ hybridization for MDM2 amplification are key to make a correct diagnosis. This is especially true if such a lesion was first noted in the lamina propria on histopathology from an endoscopic mucosal biopsy.

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