Sharon Manne, Adana A M Llanos, Hari S Iyer, Lisa E Paddock, Katie Devine, Shawna V Hudson, Denalee O'Malley, Elisa V Bandera, Sara Frederick, Jacintha Peram, Justin Solleder, Shengguo Li, Hao Liu, Andrew M Evens
{"title":"新泽西州癌症幸存者队列中与COVID-19诊断相关的社会人口统计学、医学、健康行为和心理社会因素","authors":"Sharon Manne, Adana A M Llanos, Hari S Iyer, Lisa E Paddock, Katie Devine, Shawna V Hudson, Denalee O'Malley, Elisa V Bandera, Sara Frederick, Jacintha Peram, Justin Solleder, Shengguo Li, Hao Liu, Andrew M Evens","doi":"10.1007/s10552-025-01997-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cancer survivors are more susceptible to contracting COVID-19. However, beyond race, age, and sex, less is known about other neighborhood and psychosocial factors contribute to this increased risk.</p><p><strong>Objective: </strong>The goal of this study was to examine the associations of individual and area-level social determinants of health (SDOH) measures, medical, lifestyle, and psychosocial factors and COVID-19 infection in a statewide cohort of cancer survivors in New Jersey.</p><p><strong>Methods: </strong>Survey data from 864 cancer survivors in New Jersey were collected from 2018 to 2022, which were merged with study participant data from the state of New Jersey on COVID-19 diagnoses in 2020, 2021, and 2022. We estimated adjusted odds ratios (aOR) for associations of COVID-19 diagnosis with individual-level factors (cancer type and stage, health behaviors, and psychosocial factors) and area-level SDOH [Social Vulnerability Index, Area Deprivation Index, and Index of Concentration at the Extremes (ICE) to quantify racialized deprivation vs. privilege based on income].</p><p><strong>Results: </strong>Cancer survivors born outside the US were more than twice as likely to contract COVID-19 compared to US-born survivors (aOR 2.29, 95% CI 1.01, 4.92). Compared to Quartile 4, residence in an area in Quartile 1 of racialized income ICE (i.e., predominantly Black, low income) was associated with higher odds of COVID-19 (aOR 2.15, 95% CI 0.98, 4.87). Retired survivors had lower odds of COVID-19 (aOR 0.39, 95% CI 0.19, 0.80) compared to those who were employed. Higher social well-being was associated with higher COVID-19 (aOR 1.07, 95% CI 1.02, 1.13). Type of cancer and cancer treatments received were not associated with the risk of COVID-19.</p><p><strong>Conclusions: </strong>Immigrant status and increased racialized deprivation as measured by ICE for income were associated with COVID-19. These findings support evidence that individual and area-level SDOH measures contribute to increased risk of COVID-19 among cancer survivors.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":"853-870"},"PeriodicalIF":2.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289746/pdf/","citationCount":"0","resultStr":"{\"title\":\"Sociodemographic, medical, health behavior, and psychosocial factors associated with COVID-19 diagnoses in the New Jersey cancer survivor cohort.\",\"authors\":\"Sharon Manne, Adana A M Llanos, Hari S Iyer, Lisa E Paddock, Katie Devine, Shawna V Hudson, Denalee O'Malley, Elisa V Bandera, Sara Frederick, Jacintha Peram, Justin Solleder, Shengguo Li, Hao Liu, Andrew M Evens\",\"doi\":\"10.1007/s10552-025-01997-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Cancer survivors are more susceptible to contracting COVID-19. However, beyond race, age, and sex, less is known about other neighborhood and psychosocial factors contribute to this increased risk.</p><p><strong>Objective: </strong>The goal of this study was to examine the associations of individual and area-level social determinants of health (SDOH) measures, medical, lifestyle, and psychosocial factors and COVID-19 infection in a statewide cohort of cancer survivors in New Jersey.</p><p><strong>Methods: </strong>Survey data from 864 cancer survivors in New Jersey were collected from 2018 to 2022, which were merged with study participant data from the state of New Jersey on COVID-19 diagnoses in 2020, 2021, and 2022. We estimated adjusted odds ratios (aOR) for associations of COVID-19 diagnosis with individual-level factors (cancer type and stage, health behaviors, and psychosocial factors) and area-level SDOH [Social Vulnerability Index, Area Deprivation Index, and Index of Concentration at the Extremes (ICE) to quantify racialized deprivation vs. privilege based on income].</p><p><strong>Results: </strong>Cancer survivors born outside the US were more than twice as likely to contract COVID-19 compared to US-born survivors (aOR 2.29, 95% CI 1.01, 4.92). Compared to Quartile 4, residence in an area in Quartile 1 of racialized income ICE (i.e., predominantly Black, low income) was associated with higher odds of COVID-19 (aOR 2.15, 95% CI 0.98, 4.87). Retired survivors had lower odds of COVID-19 (aOR 0.39, 95% CI 0.19, 0.80) compared to those who were employed. Higher social well-being was associated with higher COVID-19 (aOR 1.07, 95% CI 1.02, 1.13). Type of cancer and cancer treatments received were not associated with the risk of COVID-19.</p><p><strong>Conclusions: </strong>Immigrant status and increased racialized deprivation as measured by ICE for income were associated with COVID-19. 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引用次数: 0
摘要
背景：癌症幸存者更容易感染COVID-19。然而，除了种族、年龄和性别之外，人们对其他社区和社会心理因素对这种风险增加的影响知之甚少。目的：本研究的目的是研究个人和地区层面的健康社会决定因素（SDOH）措施、医疗、生活方式和社会心理因素与新泽西州全州癌症幸存者队列中COVID-19感染的关系。方法：收集2018年至2022年新泽西州864名癌症幸存者的调查数据，并将其与2020年、2021年和2022年新泽西州关于COVID-19诊断的研究参与者数据合并。我们估计了COVID-19诊断与个人水平因素（癌症类型和分期、健康行为和心理社会因素）和地区水平SDOH（社会脆弱性指数、地区剥夺指数和极端集中指数，以量化种族化剥夺与基于收入的特权）之间的关联的调整优势比（aOR）。结果：与在美国出生的幸存者相比，在美国以外出生的癌症幸存者感染COVID-19的可能性是美国出生的幸存者的两倍多（aOR 2.29, 95% CI 1.01, 4.92）。与四分位数4相比，居住在种族化收入ICE的四分位数1区域（即主要是黑人，低收入）与更高的COVID-19发病率相关（aOR 2.15, 95% CI 0.98, 4.87）。与在职人员相比，退休幸存者感染COVID-19的几率较低（aOR 0.39, 95% CI 0.19, 0.80）。较高的社会幸福感与较高的COVID-19相关（aOR 1.07, 95% CI 1.02, 1.13）。癌症类型和接受的癌症治疗与COVID-19的风险无关。结论：移民身份和ICE收入测量的种族化剥夺增加与COVID-19相关。这些发现支持了个人和地区层面的SDOH措施导致癌症幸存者中COVID-19风险增加的证据。
Sociodemographic, medical, health behavior, and psychosocial factors associated with COVID-19 diagnoses in the New Jersey cancer survivor cohort.
Background: Cancer survivors are more susceptible to contracting COVID-19. However, beyond race, age, and sex, less is known about other neighborhood and psychosocial factors contribute to this increased risk.
Objective: The goal of this study was to examine the associations of individual and area-level social determinants of health (SDOH) measures, medical, lifestyle, and psychosocial factors and COVID-19 infection in a statewide cohort of cancer survivors in New Jersey.
Methods: Survey data from 864 cancer survivors in New Jersey were collected from 2018 to 2022, which were merged with study participant data from the state of New Jersey on COVID-19 diagnoses in 2020, 2021, and 2022. We estimated adjusted odds ratios (aOR) for associations of COVID-19 diagnosis with individual-level factors (cancer type and stage, health behaviors, and psychosocial factors) and area-level SDOH [Social Vulnerability Index, Area Deprivation Index, and Index of Concentration at the Extremes (ICE) to quantify racialized deprivation vs. privilege based on income].
Results: Cancer survivors born outside the US were more than twice as likely to contract COVID-19 compared to US-born survivors (aOR 2.29, 95% CI 1.01, 4.92). Compared to Quartile 4, residence in an area in Quartile 1 of racialized income ICE (i.e., predominantly Black, low income) was associated with higher odds of COVID-19 (aOR 2.15, 95% CI 0.98, 4.87). Retired survivors had lower odds of COVID-19 (aOR 0.39, 95% CI 0.19, 0.80) compared to those who were employed. Higher social well-being was associated with higher COVID-19 (aOR 1.07, 95% CI 1.02, 1.13). Type of cancer and cancer treatments received were not associated with the risk of COVID-19.
Conclusions: Immigrant status and increased racialized deprivation as measured by ICE for income were associated with COVID-19. These findings support evidence that individual and area-level SDOH measures contribute to increased risk of COVID-19 among cancer survivors.
期刊介绍：
Cancer Causes & Control is an international refereed journal that both reports and stimulates new avenues of investigation into the causes, control, and subsequent prevention of cancer. By drawing together related information published currently in a diverse range of biological and medical journals, it has a multidisciplinary and multinational approach.
The scope of the journal includes: variation in cancer distribution within and between populations; factors associated with cancer risk; preventive and therapeutic interventions on a population scale; economic, demographic, and health-policy implications of cancer; and related methodological issues.
The emphasis is on speed of publication. The journal will normally publish within 30 to 60 days of acceptance of manuscripts.
Cancer Causes & Control publishes Original Articles, Reviews, Commentaries, Opinions, Short Communications and Letters to the Editor which will have direct relevance to researchers and practitioners working in epidemiology, medical statistics, cancer biology, health education, medical economics and related fields. The journal also contains significant information for government agencies concerned with cancer research, control and policy.
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