{"title":"化疗联合无细胞浓缩腹水回输治疗非小细胞肺癌合并大量恶性腹水1例。","authors":"Koichi Jingo, Haruki Hirakawa, Tomoyasu Mimori, Shinya Fujioka, Yuki Muto, Makiko Komaru, Manami Haba, Yoichiro Mitsuishi, Kazuhisa Takahashi","doi":"10.1111/1759-7714.70074","DOIUrl":null,"url":null,"abstract":"<p><p>We report the case of a 65-year-old woman with stage IVB lung adenocarcinoma who developed malignant ascites during treatment. Despite multiple ascitic fluid drainages and second-line chemotherapy, the ascites progressively worsened. The initiation of cell-free and concentrated ascites reinfusion therapy (CART) led to improved abdominal distention, increased blood albumin levels, and slower ascites accumulation. To our knowledge, this is the first report of CART combined with chemotherapy for the management of malignant ascites associated with lung cancer.</p>","PeriodicalId":23338,"journal":{"name":"Thoracic Cancer","volume":"16 8","pages":"e70074"},"PeriodicalIF":2.3000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021532/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Case of Non-Small-Cell Lung Cancer With Massive Malignant Ascites Treated With Chemotherapy Combined With Cell-Free and Concentrated Ascites Reinfusion Therapy.\",\"authors\":\"Koichi Jingo, Haruki Hirakawa, Tomoyasu Mimori, Shinya Fujioka, Yuki Muto, Makiko Komaru, Manami Haba, Yoichiro Mitsuishi, Kazuhisa Takahashi\",\"doi\":\"10.1111/1759-7714.70074\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We report the case of a 65-year-old woman with stage IVB lung adenocarcinoma who developed malignant ascites during treatment. Despite multiple ascitic fluid drainages and second-line chemotherapy, the ascites progressively worsened. The initiation of cell-free and concentrated ascites reinfusion therapy (CART) led to improved abdominal distention, increased blood albumin levels, and slower ascites accumulation. To our knowledge, this is the first report of CART combined with chemotherapy for the management of malignant ascites associated with lung cancer.</p>\",\"PeriodicalId\":23338,\"journal\":{\"name\":\"Thoracic Cancer\",\"volume\":\"16 8\",\"pages\":\"e70074\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021532/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Thoracic Cancer\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/1759-7714.70074\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Thoracic Cancer","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/1759-7714.70074","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
A Case of Non-Small-Cell Lung Cancer With Massive Malignant Ascites Treated With Chemotherapy Combined With Cell-Free and Concentrated Ascites Reinfusion Therapy.
We report the case of a 65-year-old woman with stage IVB lung adenocarcinoma who developed malignant ascites during treatment. Despite multiple ascitic fluid drainages and second-line chemotherapy, the ascites progressively worsened. The initiation of cell-free and concentrated ascites reinfusion therapy (CART) led to improved abdominal distention, increased blood albumin levels, and slower ascites accumulation. To our knowledge, this is the first report of CART combined with chemotherapy for the management of malignant ascites associated with lung cancer.
期刊介绍:
Thoracic Cancer aims to facilitate international collaboration and exchange of comprehensive and cutting-edge information on basic, translational, and applied clinical research in lung cancer, esophageal cancer, mediastinal cancer, breast cancer and other thoracic malignancies. Prevention, treatment and research relevant to Asia-Pacific is a focus area, but submissions from all regions are welcomed. The editors encourage contributions relevant to prevention, general thoracic surgery, medical oncology, radiology, radiation medicine, pathology, basic cancer research, as well as epidemiological and translational studies in thoracic cancer. Thoracic Cancer is the official publication of the Chinese Society of Lung Cancer, International Chinese Society of Thoracic Surgery and is endorsed by the Korean Association for the Study of Lung Cancer and the Hong Kong Cancer Therapy Society.
The Journal publishes a range of article types including: Editorials, Invited Reviews, Mini Reviews, Original Articles, Clinical Guidelines, Technological Notes, Imaging in thoracic cancer, Meeting Reports, Case Reports, Letters to the Editor, Commentaries, and Brief Reports.