低能量和高能量早期肠内营养策略对急性肾损伤患者预后的影响。

IF 2.1 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

International Journal of General Medicine Pub Date : 2025-04-21 eCollection Date: 2025-01-01 DOI:10.2147/IJGM.S505545

Ajuan Hou, Caiping Zhao

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引用次数: 0

摘要

目的：探讨不同早期肠内营养（EEN）策略对急性肾损伤（AKI）持续肾替代治疗（CRRT）患者营养指标和免疫功能的影响。方法：回顾性分析2020年1月至2024年3月60例接受crrt治疗的AKI患者，分为对照组（高能EEN）和观察组（低能EEN）。比较营养指标（白蛋白、前白蛋白、血红蛋白）、免疫功能指标（CD4+、CD8+、免疫球蛋白A、G、M）和临床结果（ICU住院时间、CRRT时间、胃潴留）。结果：治疗前，两组患者营养指标比较，差异无统计学意义（P < 0.05）。治疗7 d后，观察组患者各项营养指标均有显著性改善（P < 0.05）。观察组患者免疫功能指标也有显著改善（P < 0.05）。观察组ICU和CRRT持续时间明显短于对照组（P < 0.05）。结论：与高能EEN引导相比，低能EEN引导可显著改善crrt治疗AKI患者的营养状况，增强免疫功能。

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Impact of Low-Energy and High-Energy Early Enteral Nutrition Strategies on Patient Outcomes in Acute Kidney Injury.

Objective: To investigate the impact of different early enteral nutrition (EEN) strategies on nutritional indicators and immune function in patients with acute kidney injury (AKI) undergoing continuous renal replacement therapy (CRRT).

Methods: A retrospective analysis was conducted on 60 CRRT-treated AKI patients from January 2020 to March 2024, divided into a control group (high-energy EEN) and an observation group (low-energy EEN). Nutritional indicators (albumin, prealbumin, hemoglobin), immune function indicators (CD4+, CD8+, immunoglobulin A, G, M), and clinical outcomes (ICU stay duration, CRRT duration, gastric retention) were compared.

Results: Before treatment, there were no significant differences in nutritional indicators between the two groups (P > 0.05). After 7 days of treatment, the observation group showed significantly greater improvements in all nutritional indicators (P < 0.05). Immune function indicators also improved significantly in the observation group (P < 0.05). Additionally, the observation group had significantly shorter ICU and CRRT durations compared to the control group (P < 0.05).

Conclusion: Compared to high-energy EEN guidance, low-energy EEN guidance significantly improves nutritional status and enhances immune function in CRRT-treated AKI patients.

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来源期刊

International Journal of General Medicine Medicine-General Medicine

自引率

0.00%

发文量

1113

审稿时长

16 weeks

期刊介绍： The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal. As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.