{"title":"随着时间的推移,更频繁的失眠症状和睡眠药物的使用可能会增加晚年残疾。","authors":"Tuo-Yu Chen, Soomi Lee, Orfeu M Buxton","doi":"10.1093/sleep/zsaf098","DOIUrl":null,"url":null,"abstract":"<p><strong>Study objectives: </strong>This study investigated whether disability status increased with the frequency of insomnia symptoms and sleep medication usage over a 5-year period and whether frequent use of sleep medication modified the longitudinal effects of insomnia symptoms on disability among community-dwelling older adults.</p><p><strong>Methods: </strong>Data were from the National Health and Aging Trends Study (2011-2015; n = 6722). Disability was assessed with a validated disability index. Insomnia symptoms were assessed by the average frequency of longer sleep onset latency and trouble staying asleep. General sleep medication usage frequency was assessed. Multilevel modeling was used to analyze the data, considering health status, demographic information, and risky health behavior.</p><p><strong>Results: </strong>In the conditional growth model, for every one-unit higher in the frequency of insomnia symptoms and sleep medication usage, disability scores increased by 0.20 (SE = .02, p < .001) and 0.19 (SE = .02, p < .001) every year, respectively, adjusting for covariates. Moreover, the frequency of sleep medication usage influenced the relationship between insomnia symptoms and disability. Specifically, more frequent insomnia symptoms were associated with higher disability scores, and using sleep medications more often led to an even greater increase in disability scores than insomnia symptoms alone.</p><p><strong>Conclusions: </strong>Disability increased with more frequent insomnia symptoms and more frequent sleep medication usage each year. More frequent sleep medication usage has detrimental implications on disability beyond insomnia symptoms. Treating insomnia and managing sleep medication properly may help prevent disability among older adults.</p>","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Late-life disability may increase with more frequent insomnia symptoms and sleep medications use over time.\",\"authors\":\"Tuo-Yu Chen, Soomi Lee, Orfeu M Buxton\",\"doi\":\"10.1093/sleep/zsaf098\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study objectives: </strong>This study investigated whether disability status increased with the frequency of insomnia symptoms and sleep medication usage over a 5-year period and whether frequent use of sleep medication modified the longitudinal effects of insomnia symptoms on disability among community-dwelling older adults.</p><p><strong>Methods: </strong>Data were from the National Health and Aging Trends Study (2011-2015; n = 6722). Disability was assessed with a validated disability index. Insomnia symptoms were assessed by the average frequency of longer sleep onset latency and trouble staying asleep. General sleep medication usage frequency was assessed. Multilevel modeling was used to analyze the data, considering health status, demographic information, and risky health behavior.</p><p><strong>Results: </strong>In the conditional growth model, for every one-unit higher in the frequency of insomnia symptoms and sleep medication usage, disability scores increased by 0.20 (SE = .02, p < .001) and 0.19 (SE = .02, p < .001) every year, respectively, adjusting for covariates. Moreover, the frequency of sleep medication usage influenced the relationship between insomnia symptoms and disability. Specifically, more frequent insomnia symptoms were associated with higher disability scores, and using sleep medications more often led to an even greater increase in disability scores than insomnia symptoms alone.</p><p><strong>Conclusions: </strong>Disability increased with more frequent insomnia symptoms and more frequent sleep medication usage each year. More frequent sleep medication usage has detrimental implications on disability beyond insomnia symptoms. Treating insomnia and managing sleep medication properly may help prevent disability among older adults.</p>\",\"PeriodicalId\":22018,\"journal\":{\"name\":\"Sleep\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":4.9000,\"publicationDate\":\"2025-08-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sleep\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/sleep/zsaf098\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sleep","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/sleep/zsaf098","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
研究目的:本研究调查了在5年的时间里,残疾状况是否随着失眠症状的出现频率和睡眠药物的使用而增加,以及频繁使用睡眠药物是否会改变社区居住老年人失眠症状对残疾的纵向影响。方法:数据来源于2011-2015年全国健康与老龄化趋势研究;n = 6722)。用有效的残疾指数评估残疾。失眠症状是通过较长睡眠潜伏期的平均频率和难以保持睡眠来评估的。评估一般睡眠药物的使用频率。考虑健康状况、人口统计信息和危险健康行为,采用多层次模型对数据进行分析。结果:在条件生长模型中,经协变量调整后,失眠症状出现频率和睡眠药物使用频率每增加1个单位,残疾评分每年分别增加0.20 (SE = 0.02, p < 0.001)和0.19 (SE = 0.02, p < 0.001)。此外,睡眠药物的使用频率影响失眠症状与残疾的关系。具体来说,更频繁的失眠症状与更高的残疾评分相关,而更频繁地使用睡眠药物会导致残疾评分的增加,而不仅仅是失眠症状。结论:残疾随着失眠症状和睡眠药物使用频率的增加而增加。更频繁地使用睡眠药物,除了失眠症状外,还会对残疾产生有害影响。适当治疗失眠和管理睡眠药物可能有助于预防老年人的残疾。
Late-life disability may increase with more frequent insomnia symptoms and sleep medications use over time.
Study objectives: This study investigated whether disability status increased with the frequency of insomnia symptoms and sleep medication usage over a 5-year period and whether frequent use of sleep medication modified the longitudinal effects of insomnia symptoms on disability among community-dwelling older adults.
Methods: Data were from the National Health and Aging Trends Study (2011-2015; n = 6722). Disability was assessed with a validated disability index. Insomnia symptoms were assessed by the average frequency of longer sleep onset latency and trouble staying asleep. General sleep medication usage frequency was assessed. Multilevel modeling was used to analyze the data, considering health status, demographic information, and risky health behavior.
Results: In the conditional growth model, for every one-unit higher in the frequency of insomnia symptoms and sleep medication usage, disability scores increased by 0.20 (SE = .02, p < .001) and 0.19 (SE = .02, p < .001) every year, respectively, adjusting for covariates. Moreover, the frequency of sleep medication usage influenced the relationship between insomnia symptoms and disability. Specifically, more frequent insomnia symptoms were associated with higher disability scores, and using sleep medications more often led to an even greater increase in disability scores than insomnia symptoms alone.
Conclusions: Disability increased with more frequent insomnia symptoms and more frequent sleep medication usage each year. More frequent sleep medication usage has detrimental implications on disability beyond insomnia symptoms. Treating insomnia and managing sleep medication properly may help prevent disability among older adults.
期刊介绍:
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