Oleksiy V Voytsekhivskyy,Kenneth J Hoffer,David L Cooke,Giacomo Savini
{"title":"人工晶状体度数计算项目:36个公式的准确性。","authors":"Oleksiy V Voytsekhivskyy,Kenneth J Hoffer,David L Cooke,Giacomo Savini","doi":"10.1016/j.ajo.2025.05.004","DOIUrl":null,"url":null,"abstract":"PURPOSE\r\nTo ascertain the refractive accuracy of 36 intraocular lens (IOL) power calculation formulas in unoperated eyes.\r\n\r\nDESIGN\r\nRetrospective accuracy and validity analysis.\r\n\r\nPARTICIPANTS\r\nSix hundred fifty-five patients undergoing phacoemulsification and implantation of the Tecnis 1 ZCB00 IOL (Johnson & Johnson Vision, Jacksonville, FL, USA).\r\n\r\nMETHODS\r\nThirty-six formulas were evaluated including some that have never been tested, such as 3C 2.0, Eom, Hoffer H, Hoffer H-5, Fam adjusted methods, Norrby Regression Formula (Norrby RF), Norrby thin lens paraxial Ray-Tracing (Norrby RT), and VRF Cooke modified axial length (VRF CMAL). Optical biometry with the IOLMaster 700 (Carl Zeiss Meditec AG) was performed preoperatively. All descriptive statistics and the percentage of eyes within prediction error thresholds were evaluated with optimized lens constants.\r\n\r\nMAIN OUTCOME MEASURES\r\nThe Formula Performance Index (FPI) and Formula Performance Index for subgroup (FPI sub) were used as the primary formula outcomes.\r\n\r\nRESULTS\r\nThe highest FPI indexes were yielded by the VRF-G (0.590), Hoffer QST (0.575), VRF CMAL (0.574), Eom (0.572), EVO 2.0 (0.569), and Kane (0.568) formulas. The heteroscedastic test revealed statistically significant differences (P < 0.05) among formulas. The standard deviation (SD) of VRF-G (0.353 D), EVO 2.0 (0.362 D), Kane (0.366 D), Hoffer QST (0.371 D), and Eom (0.372 D) were lower than other methods (P < 0.05). The highest percentage of eyes with a PE within ±0.50 D was achieved by VRF-G (87.48%), Kane (86.41%), Hoffer QST (86.26%), and PEARL-DGS (86.26%).\r\n\r\nCONCLUSION\r\nContemporary IOL power calculation formulas (Eom, EVO 2.0, Hoffer QST, VRF CMAL, and VRF-G) improved accuracy in all axial length ranges compared to traditional and updated methods. The CMAL method raised the accuracy of the VRF formula.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"148 1","pages":""},"PeriodicalIF":4.1000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"IOL power calculation project: accuracy of 36 formulas.\",\"authors\":\"Oleksiy V Voytsekhivskyy,Kenneth J Hoffer,David L Cooke,Giacomo Savini\",\"doi\":\"10.1016/j.ajo.2025.05.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"PURPOSE\\r\\nTo ascertain the refractive accuracy of 36 intraocular lens (IOL) power calculation formulas in unoperated eyes.\\r\\n\\r\\nDESIGN\\r\\nRetrospective accuracy and validity analysis.\\r\\n\\r\\nPARTICIPANTS\\r\\nSix hundred fifty-five patients undergoing phacoemulsification and implantation of the Tecnis 1 ZCB00 IOL (Johnson & Johnson Vision, Jacksonville, FL, USA).\\r\\n\\r\\nMETHODS\\r\\nThirty-six formulas were evaluated including some that have never been tested, such as 3C 2.0, Eom, Hoffer H, Hoffer H-5, Fam adjusted methods, Norrby Regression Formula (Norrby RF), Norrby thin lens paraxial Ray-Tracing (Norrby RT), and VRF Cooke modified axial length (VRF CMAL). Optical biometry with the IOLMaster 700 (Carl Zeiss Meditec AG) was performed preoperatively. All descriptive statistics and the percentage of eyes within prediction error thresholds were evaluated with optimized lens constants.\\r\\n\\r\\nMAIN OUTCOME MEASURES\\r\\nThe Formula Performance Index (FPI) and Formula Performance Index for subgroup (FPI sub) were used as the primary formula outcomes.\\r\\n\\r\\nRESULTS\\r\\nThe highest FPI indexes were yielded by the VRF-G (0.590), Hoffer QST (0.575), VRF CMAL (0.574), Eom (0.572), EVO 2.0 (0.569), and Kane (0.568) formulas. The heteroscedastic test revealed statistically significant differences (P < 0.05) among formulas. The standard deviation (SD) of VRF-G (0.353 D), EVO 2.0 (0.362 D), Kane (0.366 D), Hoffer QST (0.371 D), and Eom (0.372 D) were lower than other methods (P < 0.05). The highest percentage of eyes with a PE within ±0.50 D was achieved by VRF-G (87.48%), Kane (86.41%), Hoffer QST (86.26%), and PEARL-DGS (86.26%).\\r\\n\\r\\nCONCLUSION\\r\\nContemporary IOL power calculation formulas (Eom, EVO 2.0, Hoffer QST, VRF CMAL, and VRF-G) improved accuracy in all axial length ranges compared to traditional and updated methods. The CMAL method raised the accuracy of the VRF formula.\",\"PeriodicalId\":7568,\"journal\":{\"name\":\"American Journal of Ophthalmology\",\"volume\":\"148 1\",\"pages\":\"\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2025-05-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.ajo.2025.05.004\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ajo.2025.05.004","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
IOL power calculation project: accuracy of 36 formulas.
PURPOSE
To ascertain the refractive accuracy of 36 intraocular lens (IOL) power calculation formulas in unoperated eyes.
DESIGN
Retrospective accuracy and validity analysis.
PARTICIPANTS
Six hundred fifty-five patients undergoing phacoemulsification and implantation of the Tecnis 1 ZCB00 IOL (Johnson & Johnson Vision, Jacksonville, FL, USA).
METHODS
Thirty-six formulas were evaluated including some that have never been tested, such as 3C 2.0, Eom, Hoffer H, Hoffer H-5, Fam adjusted methods, Norrby Regression Formula (Norrby RF), Norrby thin lens paraxial Ray-Tracing (Norrby RT), and VRF Cooke modified axial length (VRF CMAL). Optical biometry with the IOLMaster 700 (Carl Zeiss Meditec AG) was performed preoperatively. All descriptive statistics and the percentage of eyes within prediction error thresholds were evaluated with optimized lens constants.
MAIN OUTCOME MEASURES
The Formula Performance Index (FPI) and Formula Performance Index for subgroup (FPI sub) were used as the primary formula outcomes.
RESULTS
The highest FPI indexes were yielded by the VRF-G (0.590), Hoffer QST (0.575), VRF CMAL (0.574), Eom (0.572), EVO 2.0 (0.569), and Kane (0.568) formulas. The heteroscedastic test revealed statistically significant differences (P < 0.05) among formulas. The standard deviation (SD) of VRF-G (0.353 D), EVO 2.0 (0.362 D), Kane (0.366 D), Hoffer QST (0.371 D), and Eom (0.372 D) were lower than other methods (P < 0.05). The highest percentage of eyes with a PE within ±0.50 D was achieved by VRF-G (87.48%), Kane (86.41%), Hoffer QST (86.26%), and PEARL-DGS (86.26%).
CONCLUSION
Contemporary IOL power calculation formulas (Eom, EVO 2.0, Hoffer QST, VRF CMAL, and VRF-G) improved accuracy in all axial length ranges compared to traditional and updated methods. The CMAL method raised the accuracy of the VRF formula.
期刊介绍:
The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect.
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