{"title":"ETDQ-7评分在评估ETD中的作用。","authors":"Niels Højvang Holm, Therese Ovesen","doi":"10.1111/coa.14324","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p>The ETDQ-7 questionnaire has been validated for diagnosing Eustachian tube dysfunction (ETD) and a minimal clinically important difference (MCID) of > 3.5 has been suggested. We aim to assess the use of ETDQ-7 for assessing ETD and a potential correlation between ETDQ-7 and the Sino-Nasal Outcome Test 22 (SNOT-22).</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>ETD was based on relevant ear symptoms and objective signs of negative middle ear pressure in 75 consecutive adult patients. Ventilation tube insertion (VTi) was performed on affected ears. ETDQ-7 and SNOT-22 scores before and 1 month after VTi were compared to 75 healthy controls.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Mean ETDQ-7 score decreased from 31.9 to 15.8 (<i>p</i> < 0.0001), remained stable on unaffected ears, and was 9.6 in controls. MCID was achieved on all affected ears after VTi. A cut-off score of > 14.5 for diagnosing ETD yielded 100% sensitivity and 94.2% specificity for ETDQ-7. Spearman's <i>ρ</i> for total score test–retest was 0.878 (<i>p</i> = 0.000). Cronbach alpha for total score varied from 0.6807 to 0.7266. SNOT-22 and ETDQ-7 were correlated at baseline (0.12, <i>p</i> = 0.012). ETD patients scored significantly higher in the nasal, otologic and sleep domains in SNOT-22 compared to controls.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>ETDQ-7 is a very valid tool for ETD diagnostics and assessing the ear-related effects of VTi. ETDQ-7 scores reveal residual symptoms after VTi, indicating symptom relief but no cure for the underlying pathophysiology. For future investigation, we suggest assessing ETDQ-7 scores for each ear separately, higher MCID values, and integration of quality of life measures.</p>\n \n <p>\n <b>Trial Registration:</b> ClinicalTrials.gov: NCT05055115</p>\n </section>\n </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"50 5","pages":"840-847"},"PeriodicalIF":1.5000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.14324","citationCount":"0","resultStr":"{\"title\":\"The Usefulness of ETDQ-7 Score in Assessing ETD\",\"authors\":\"Niels Højvang Holm, Therese Ovesen\",\"doi\":\"10.1111/coa.14324\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Introduction</h3>\\n \\n <p>The ETDQ-7 questionnaire has been validated for diagnosing Eustachian tube dysfunction (ETD) and a minimal clinically important difference (MCID) of > 3.5 has been suggested. We aim to assess the use of ETDQ-7 for assessing ETD and a potential correlation between ETDQ-7 and the Sino-Nasal Outcome Test 22 (SNOT-22).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>ETD was based on relevant ear symptoms and objective signs of negative middle ear pressure in 75 consecutive adult patients. Ventilation tube insertion (VTi) was performed on affected ears. ETDQ-7 and SNOT-22 scores before and 1 month after VTi were compared to 75 healthy controls.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Mean ETDQ-7 score decreased from 31.9 to 15.8 (<i>p</i> < 0.0001), remained stable on unaffected ears, and was 9.6 in controls. MCID was achieved on all affected ears after VTi. A cut-off score of > 14.5 for diagnosing ETD yielded 100% sensitivity and 94.2% specificity for ETDQ-7. Spearman's <i>ρ</i> for total score test–retest was 0.878 (<i>p</i> = 0.000). Cronbach alpha for total score varied from 0.6807 to 0.7266. SNOT-22 and ETDQ-7 were correlated at baseline (0.12, <i>p</i> = 0.012). ETD patients scored significantly higher in the nasal, otologic and sleep domains in SNOT-22 compared to controls.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>ETDQ-7 is a very valid tool for ETD diagnostics and assessing the ear-related effects of VTi. ETDQ-7 scores reveal residual symptoms after VTi, indicating symptom relief but no cure for the underlying pathophysiology. For future investigation, we suggest assessing ETDQ-7 scores for each ear separately, higher MCID values, and integration of quality of life measures.</p>\\n \\n <p>\\n <b>Trial Registration:</b> ClinicalTrials.gov: NCT05055115</p>\\n </section>\\n </div>\",\"PeriodicalId\":10431,\"journal\":{\"name\":\"Clinical Otolaryngology\",\"volume\":\"50 5\",\"pages\":\"840-847\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.14324\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Otolaryngology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/coa.14324\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Otolaryngology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/coa.14324","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
The ETDQ-7 questionnaire has been validated for diagnosing Eustachian tube dysfunction (ETD) and a minimal clinically important difference (MCID) of > 3.5 has been suggested. We aim to assess the use of ETDQ-7 for assessing ETD and a potential correlation between ETDQ-7 and the Sino-Nasal Outcome Test 22 (SNOT-22).
Methods
ETD was based on relevant ear symptoms and objective signs of negative middle ear pressure in 75 consecutive adult patients. Ventilation tube insertion (VTi) was performed on affected ears. ETDQ-7 and SNOT-22 scores before and 1 month after VTi were compared to 75 healthy controls.
Results
Mean ETDQ-7 score decreased from 31.9 to 15.8 (p < 0.0001), remained stable on unaffected ears, and was 9.6 in controls. MCID was achieved on all affected ears after VTi. A cut-off score of > 14.5 for diagnosing ETD yielded 100% sensitivity and 94.2% specificity for ETDQ-7. Spearman's ρ for total score test–retest was 0.878 (p = 0.000). Cronbach alpha for total score varied from 0.6807 to 0.7266. SNOT-22 and ETDQ-7 were correlated at baseline (0.12, p = 0.012). ETD patients scored significantly higher in the nasal, otologic and sleep domains in SNOT-22 compared to controls.
Conclusion
ETDQ-7 is a very valid tool for ETD diagnostics and assessing the ear-related effects of VTi. ETDQ-7 scores reveal residual symptoms after VTi, indicating symptom relief but no cure for the underlying pathophysiology. For future investigation, we suggest assessing ETDQ-7 scores for each ear separately, higher MCID values, and integration of quality of life measures.
期刊介绍:
Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with:
current otorhinolaryngological practice
audiology, otology, balance, rhinology, larynx, voice and paediatric ORL
head and neck oncology
head and neck plastic and reconstructive surgery
continuing medical education and ORL training
The emphasis is on high quality new work in the clinical field and on fresh, original research.
Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject.
• Negative/null results
In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.