吡拉西坦有助于颅脑外伤后恢复视力。

Q4 Medicine
Georgian medical news Pub Date : 2025-02-01
M Saidulaev, N Osipova, A Gurtskaya, N Semov, R Khusainov, E Khabarov, D Lech, P Stotland, V Eloeva, A Syromyatnikova
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引用次数: 0

摘要

本文探讨吡拉西坦对脑损伤后视觉功能的影响。该药物可用于恢复颅脑外伤后的视镜改变,有助于改善大脑活动和神经可塑性。值得注意的是,吡拉西坦的疗效可能取决于损伤的严重程度以及患者的一般情况。该研究的对象是在NWSMU以I.I.Mechnikova命名的创伤性脑损伤治疗了三年的患者,他们服用吡拉西坦4周。根据颅脑外伤的严重程度,这是用格拉斯哥昏迷量表确定的,受试者被分为三组:第1组,谁曾遭受过轻度脑震荡,评级13-15分(n=20),第2组,谁有中度严重程度的创伤性脑损伤,9-12分(n=20)和第3组,这是一个安慰剂控制(n=20)。在研究之前,所有参与者都在视野的指定点上评估了他们的亮度敏感阈值(LST)和视觉运动反应时间(VMRT)。这些参数是用彩色弧度法评估的,这使我们能够在一般(0- 210)和黄斑(0- 50)和周围(5- 210)视网膜区域分别考虑这些参数。结果进行统计处理(学生标准和符号标准)。吡拉西坦给药结束时,重新评估视觉功能,即通过LST和VMRT的大小来确定视网膜的功能容量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PIRACETAM HELPS RESTORE VISION AFTER CRANIOCEREBRAL TRAUMA.

This article examines the effect of piracetam on visual function after brain injury. This drug may be useful in restoring ophthalmoscopic changes after craniocerebral trauma, contributing to improved brain activity and neuroplasticity. It is important to note that the efficacy of piracetam may depend on the severity of the injury as well as the general condition of the patient. The object of the study was patients treated at NWSMU named after I.I.Mechnikova for traumatic brain injury over the last three years, who received piracetam for 4 weeks. Depending on the severity of craniocerebral trauma, which was determined using the Glasgow Coma Scale, the subjects were divided into three groups: group №1, who had previously suffered a mild concussion, rated 13-15 points (n=20), group № 2, who had a moderate degree of severity of traumatic brain injury, 9-12 points (n=20) and group № 3, which was a placebo control (n=20). Prior to the study, all participants had their luminance sensitivity threshold (LST) and visual-motor reaction time (VMRT) assessed at specified points in the visual field. These parameters were assessed using colour campimetry, which allowed us to consider these parameters both in general (0-21o) and separately in the macular (0-5o) and peripheral (5-21o) retinal zones. The results were subjected to statistical processing (Student's and sign criteria). At the end of the course of piracetam administration, the visual functions were reassessed, namely, the functional capacity of the retina was determined by the magnitude of LST and VMRT.

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来源期刊
Georgian medical news
Georgian medical news Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
207
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