大脑发育中的压力和性别差异。

4区 医学 Q3 Neuroscience
Progress in brain research Pub Date : 2025-01-01 Epub Date: 2025-04-02 DOI:10.1016/bs.pbr.2025.01.013
Abraham Olufemi Asuku, Priscilla Omobonke Adebayo, Gbonjubola Oyinlola Ogungbangbe
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引用次数: 0

摘要

本章调查了男性和女性大脑在早期发育过程中受到压力影响的不同方式,这反过来又影响了每个群体对压力相关疾病的易感性。在检查大脑的结构和功能时,必须考虑到性别差异和压力。男性和女性大脑发育对产前睾丸分泌雄激素的反应不同。研究表明,在应对压力、编码记忆、感受情绪、解决具体问题和做出决定时,男性和女性使用的大脑区域是不同的。研究结果显示,压力会导致大脑结构和功能的特定变化,并存在性别差异。前额皮质、海马体和杏仁核是大脑中与压力反应有关的区域。应激反应与许多精神和心身疾病的表现有关。男性和女性应对压力的方式在生理和心理层面上有所不同。为了更深入地了解大脑发育过程中的性别差异,还必须对这些差异进行调查。本章暗示,应解决性别特定的脆弱性问题,并应通过与压力有关的干预措施促进健康的大脑发育。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stress and gender differences in brain development.

This chapter investigates the ways in which male and female brains are differently affected by stress during early development, which in turn affects how susceptible each group is to stress-related illnesses. When examining the structure and function of the brain, gender differences and stress must be taken into account. Male and female brain development differs in response to the prenatal testis's secretion of androgen. It appears that when it comes to responding to stress, encoding memories, feeling emotions, solving specific issues, and making decisions, men and women use distinct areas of the brain. Findings revealed that stress led to specific changes in brain structure and function, with gender-specific differences observed. The prefrontal cortex, the hippocampus, and the amygdala are among the brain regions connected to the stress response. The stress response has been linked to the presentation of numerous mental and psychosomatic conditions. The way men and women respond to stress varies on a biological and psychological level. To gain more insight into the gender differences seen throughout brain development, these disparities must also be investigated. This chapter implies that gender-specific vulnerabilities should be addressed and healthy brain development should be promoted by stress-related interventions.

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来源期刊
Progress in brain research
Progress in brain research 医学-神经科学
CiteScore
5.20
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
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