Benjamin L Petrykowski, Conner Thompson, Tiffany G Baker, Cynthia T Welsh
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Clival Chordoma Metastatic to Lymph Node: Brachyury Staining Insights.
Clival chordomas are rare bone tumors involving the primary intracranial central nervous system. These tumors reoccur and invade locally but metastasis is uncommon. We present a 54-year-old woman with a 10-year recurrence of a conventional chordoma originating from the clivus with lymph node metastasis that was confirmed with brachyury. Based on our review of the literature, there have been only 3 confirmed patients with clival chordoma metastasis to lymph nodes and this is the first account of a conventional chordoma lymph node metastasis being confirmed with brachyury immunohistochemistry.
期刊介绍:
International Journal of Surgical Pathology (IJSP) is a peer-reviewed journal published eight times a year, which offers original research and observations covering all major organ systems, timely reviews of new techniques and procedures, discussions of controversies in surgical pathology, case reports, and images in pathology. This journal is a member of the Committee on Publication Ethics (COPE).