成人不同健康结果的最佳保护性25-羟基维生素D水平：剂量-反应荟萃分析的简要总结

IF 3.4 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Metabolites Pub Date : 2025-04-10 DOI:10.3390/metabo15040264

Cem Ekmekcioglu, Michael Poteser

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引用次数: 0

摘要

维生素D对骨骼代谢非常重要，对预防各种疾病也很重要，比如2型糖尿病、心血管疾病和不同类型的癌症。尽管维生素D缺乏是一个普遍存在的重要公共卫生问题，但科学界存在争议，对维生素D充足和缺乏状态没有既定的标准定义。为了增加关于这一主题的新信息，这篇简短的意见论文的目的是通过总结剂量-反应报告荟萃分析，确定和讨论降低各种疾病结局风险的最佳25(OH)D浓度（范围）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Optimal Protective 25-Hydroxyvitamin D Level for Different Health Outcomes in Adults: A Brief Summary of Dose-Response Meta-Analyses.

Vitamin D is very important for bone metabolism as well as for the prevention of various diseases, such as type 2 diabetes, cardiovascular disease and different types of cancer. Although vitamin D deficiency is widespread and an important public health problem, there exists controversy in the scientific community, with no established standard definition of adequate and deficient vitamin D status. To add new information on this topic, the aim of this brief opinion paper is to identify and discuss the optimal 25(OH)D concentration (range) for a reduction in the risk of various disease outcomes by summarizing dose-response reporting meta-analyses.

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来源期刊

Metabolites Biochemistry, Genetics and Molecular Biology-Molecular Biology

CiteScore

5.70

自引率

7.30%

发文量

1070

审稿时长

17.17 days

期刊介绍： Metabolites (ISSN 2218-1989) is an international, peer-reviewed open access journal of metabolism and metabolomics. Metabolites publishes original research articles and review articles in all molecular aspects of metabolism relevant to the fields of metabolomics, metabolic biochemistry, computational and systems biology, biotechnology and medicine, with a particular focus on the biological roles of metabolites and small molecule biomarkers. Metabolites encourages scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on article length. Sufficient experimental details must be provided to enable the results to be accurately reproduced. Electronic material representing additional figures, materials and methods explanation, or supporting results and evidence can be submitted with the main manuscript as supplementary material.