Assessment of Health-Related Quality of Life and Its Associated Factors Among Cardiovascular Disease Patients at a Teaching Hospital in Northwest Ethiopia: A Cross-Sectional Study.

Background: Health-related quality of life (HRQoL) has become a widely recognized outcome measure to assess the impact of illnesses or effectiveness of treatments. This study was carried out to investigate HRQoL and associated factors among cardiovascular disease patients. Method: This is a cross-sectional study and was carried out from July 01 to August 30, 2021. The patients were recruited using systematic random sampling technique and data was collected using EQ-5D five-level (EQ-5D-5L) questionnaires and EQ visual analog scale (EQ VAS). Utility index values were calculated using disutility weights set in Ethiopian context. Mann-Whitney U and Kruskal-Wallis tests were employed to compare the median index values and EQ VAS scores across subgroups. Tobit regression analysis was performed to determine factors associated with HRQoL. Results: Performing usual activities (76.8%) and pain/discomfort (74.9%) were the first and the second dimensions of most frequently reported health problems, respectively. The overall median (interquartile range) EQ-5D-5L index value and VAS score were 0.82 (0.65-0.92) and 70.0 (60.0-80.0), respectively. Older age, multiple CVD diagnoses, and adherence problems to medications were found to be negatively associated with HRQoL. Conclusion: In conclusion, performing usual activities and pain/discomfort were the dimensions with the most frequently reported problems. This finding dictates the importance of giving special attention to these dimensions in managing CVD patients. Besides, older age, multiple CVDs, and nonadherence to medications were negatively associated with HRQoL. Thus, acting in consideration of these factors in patient management may have positive implications in improving their HRQoL.