Gurmeet Singh, Ramadhan Karsono, Soedarman Sjamsoe, Muhammad Rizki Triono, Rina La Distia Nora, Devi Felicia, Fajar Lamhot Gultom, Daniel Ruslim, Arif Sejati, Ralph Girson Gunarsa, Ceva Wicaksono Pitoyo, Cleopas Martin Rumende
{"title":"诊断坏死性肉芽肿病的挑战:印度尼西亚首例报道。","authors":"Gurmeet Singh, Ramadhan Karsono, Soedarman Sjamsoe, Muhammad Rizki Triono, Rina La Distia Nora, Devi Felicia, Fajar Lamhot Gultom, Daniel Ruslim, Arif Sejati, Ralph Girson Gunarsa, Ceva Wicaksono Pitoyo, Cleopas Martin Rumende","doi":"10.1155/carm/3219868","DOIUrl":null,"url":null,"abstract":"<p><p>Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2025 ","pages":"3219868"},"PeriodicalIF":0.8000,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011462/pdf/","citationCount":"0","resultStr":"{\"title\":\"Challenges in Diagnosing Necrotizing Sarcoid Granulomatosis: The First Case Reported From Indonesia.\",\"authors\":\"Gurmeet Singh, Ramadhan Karsono, Soedarman Sjamsoe, Muhammad Rizki Triono, Rina La Distia Nora, Devi Felicia, Fajar Lamhot Gultom, Daniel Ruslim, Arif Sejati, Ralph Girson Gunarsa, Ceva Wicaksono Pitoyo, Cleopas Martin Rumende\",\"doi\":\"10.1155/carm/3219868\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.</p>\",\"PeriodicalId\":9627,\"journal\":{\"name\":\"Case Reports in Medicine\",\"volume\":\"2025 \",\"pages\":\"3219868\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-04-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011462/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/carm/3219868\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/carm/3219868","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Challenges in Diagnosing Necrotizing Sarcoid Granulomatosis: The First Case Reported From Indonesia.
Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.