Mohammad Budiyanto, Fasih B Ilhami, Andika P Wardana, Nora Ertanti, Sapti Puspitarini
{"title":"制作以氧化锌为复合材料装饰的梅尼兰衍生碳提取物,有效治疗癌症。","authors":"Mohammad Budiyanto, Fasih B Ilhami, Andika P Wardana, Nora Ertanti, Sapti Puspitarini","doi":"10.4149/gpb_2025003","DOIUrl":null,"url":null,"abstract":"<p><p>The development of new composite materials derived from plant-based carbon for biomedical applications has posed a considerable challenge over the past decades. Herein, we successfully designed and synthesized ZnO/Meniran-C from Meniran-derived carbon (Meniran-C) decorated on zinc oxide for effective cancer treatment. These composites showed crystal microparticles and provided unique optical properties with high absorbance compared to pure Meniran and ZnO under an aqueous solution which has the potential for increased electron-hole. More importantly, in vitro analysis of MDA-MB-231 cells as breast cancer cells exhibited high toxicity after incubation with ZnO/Meniran-C for 24 h, in comparison with incubation with Meniran only. Hence, these composite materials provide a novel composite from bioactive compounds Meniran-derived carbon with excellent anticancer therapy and offer significant potential to contribute to the development of cost-effective, environmentally friendly, and widely applicable cancer therapies for future applications.</p>","PeriodicalId":12514,"journal":{"name":"General physiology and biophysics","volume":"44 3","pages":"227-234"},"PeriodicalIF":1.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Crafting extract of Meniran-derived carbon decorated on zinc oxide as composite material for effective cancer treatment.\",\"authors\":\"Mohammad Budiyanto, Fasih B Ilhami, Andika P Wardana, Nora Ertanti, Sapti Puspitarini\",\"doi\":\"10.4149/gpb_2025003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The development of new composite materials derived from plant-based carbon for biomedical applications has posed a considerable challenge over the past decades. Herein, we successfully designed and synthesized ZnO/Meniran-C from Meniran-derived carbon (Meniran-C) decorated on zinc oxide for effective cancer treatment. These composites showed crystal microparticles and provided unique optical properties with high absorbance compared to pure Meniran and ZnO under an aqueous solution which has the potential for increased electron-hole. More importantly, in vitro analysis of MDA-MB-231 cells as breast cancer cells exhibited high toxicity after incubation with ZnO/Meniran-C for 24 h, in comparison with incubation with Meniran only. Hence, these composite materials provide a novel composite from bioactive compounds Meniran-derived carbon with excellent anticancer therapy and offer significant potential to contribute to the development of cost-effective, environmentally friendly, and widely applicable cancer therapies for future applications.</p>\",\"PeriodicalId\":12514,\"journal\":{\"name\":\"General physiology and biophysics\",\"volume\":\"44 3\",\"pages\":\"227-234\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"General physiology and biophysics\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.4149/gpb_2025003\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"General physiology and biophysics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.4149/gpb_2025003","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Crafting extract of Meniran-derived carbon decorated on zinc oxide as composite material for effective cancer treatment.
The development of new composite materials derived from plant-based carbon for biomedical applications has posed a considerable challenge over the past decades. Herein, we successfully designed and synthesized ZnO/Meniran-C from Meniran-derived carbon (Meniran-C) decorated on zinc oxide for effective cancer treatment. These composites showed crystal microparticles and provided unique optical properties with high absorbance compared to pure Meniran and ZnO under an aqueous solution which has the potential for increased electron-hole. More importantly, in vitro analysis of MDA-MB-231 cells as breast cancer cells exhibited high toxicity after incubation with ZnO/Meniran-C for 24 h, in comparison with incubation with Meniran only. Hence, these composite materials provide a novel composite from bioactive compounds Meniran-derived carbon with excellent anticancer therapy and offer significant potential to contribute to the development of cost-effective, environmentally friendly, and widely applicable cancer therapies for future applications.
期刊介绍:
General Physiology and Biophysics is devoted to the publication of original research papers concerned with general physiology, biophysics and biochemistry at the cellular and molecular level and is published quarterly by the Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences.