制作以氧化锌为复合材料装饰的梅尼兰衍生碳提取物,有效治疗癌症。

IF 1.3 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Mohammad Budiyanto, Fasih B Ilhami, Andika P Wardana, Nora Ertanti, Sapti Puspitarini
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引用次数: 0

摘要

在过去的几十年里,从植物基碳中提取用于生物医学应用的新型复合材料的开发提出了相当大的挑战。本文成功地设计并合成了氧化锌修饰的meniran -衍生碳(Meniran-C)氧化锌/Meniran-C氧化锌/Meniran-C氧化锌/Meniran-C氧化锌。与纯Meniran和ZnO相比,这些复合材料在水溶液中具有晶体微粒和高吸光度的独特光学性能,具有增加电子空穴的潜力。更重要的是,在体外分析中,MDA-MB-231细胞作为乳腺癌细胞,在与ZnO/Meniran- c孵育24小时后,与仅与Meniran孵育相比,显示出高毒性。因此,这些复合材料提供了一种新型的由生物活性化合物美尼兰衍生碳组成的复合材料,具有良好的抗癌效果,为未来开发具有成本效益、环境友好、广泛应用的癌症治疗方法提供了巨大的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Crafting extract of Meniran-derived carbon decorated on zinc oxide as composite material for effective cancer treatment.

The development of new composite materials derived from plant-based carbon for biomedical applications has posed a considerable challenge over the past decades. Herein, we successfully designed and synthesized ZnO/Meniran-C from Meniran-derived carbon (Meniran-C) decorated on zinc oxide for effective cancer treatment. These composites showed crystal microparticles and provided unique optical properties with high absorbance compared to pure Meniran and ZnO under an aqueous solution which has the potential for increased electron-hole. More importantly, in vitro analysis of MDA-MB-231 cells as breast cancer cells exhibited high toxicity after incubation with ZnO/Meniran-C for 24 h, in comparison with incubation with Meniran only. Hence, these composite materials provide a novel composite from bioactive compounds Meniran-derived carbon with excellent anticancer therapy and offer significant potential to contribute to the development of cost-effective, environmentally friendly, and widely applicable cancer therapies for future applications.

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来源期刊
General physiology and biophysics
General physiology and biophysics 生物-生化与分子生物学
CiteScore
2.70
自引率
0.00%
发文量
42
审稿时长
6-12 weeks
期刊介绍: General Physiology and Biophysics is devoted to the publication of original research papers concerned with general physiology, biophysics and biochemistry at the cellular and molecular level and is published quarterly by the Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences.
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