评估在牙周炎患者中使用浸有0.2%透明质酸凝胶的牙间刷对临床牙周参数的影响：一项随机对照试验。

IF 2.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

BMC Oral Health Pub Date : 2025-04-25 DOI:10.1186/s12903-025-06038-7

Özlem Saraç Atagün, Seval Ceylan Şen, Gülbahar Ustaoğlu, Erkan Özcan

{"title":"评估在牙周炎患者中使用浸有0.2%透明质酸凝胶的牙间刷对临床牙周参数的影响：一项随机对照试验。","authors":"Özlem Saraç Atagün, Seval Ceylan Şen, Gülbahar Ustaoğlu, Erkan Özcan","doi":"10.1186/s12903-025-06038-7","DOIUrl":null,"url":null,"abstract":"Background: The additional use of agents with antibacterial and anti-inflammatory activities, such as hyaluronic acid in treating periodontal disease, has recently become popular. This study aimed to evaluate the effects of using an interdental brush dipped in 0.2% HA gel on clinical periodontal parameters.Methods: This randomized controlled trial was conducted among 60 patients with stages II/III grades A/B periodontitis. After full-mouth scaling root planning and oral hygiene training, the patients were divided into two groups; the test group was asked to use an interdental brush dipped in 0.2% HA, while the control group was asked to use a regular interdental brush. Clinical periodontal parameters [ gingival index (GI), plaque index (PI), papillary bleeding index (PBI), pocket depth (PD), and clinical attachment loss (CAL) ] were assessed at baseline and in the 1st and 3rd months after treatment.Results: Clinical periodontal parameters were improved in control and test groups at the 1 and 3-month compared to baseline (p < 0.05). The 1st- and 3rd-month PBIs were significantly lower in the test group (p < 0.05). There was no significant difference between the test and control groups regarding PI, PD, GI, and CAL between the follow-up times.Conclusions: Although the clinical efficacy of the tested methods of interdental brush use was similar, it can be concluded that the use of an interdental brush dipped in HA may contribute to the reduction of gingival bleeding in the early period.Clinical significance: Incorporating HA into the oral hygiene regime after periodontitis treatment using an interdental brush is a useful and practical method. NAME OF THE REGISTRY: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT06309797.Date of registration: 07/03/2024 \"Retrospectively registered\". URL: https://clinicaltrials.gov/study/NCT06309797.","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"635"},"PeriodicalIF":2.6000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023370/pdf/","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the effects of using an interdental brush dipped in 0.2% hyaluronic acid gel on clinical periodontal parameters among patients with periodontitis: a randomized controlled trial.\",\"authors\":\"Özlem Saraç Atagün, Seval Ceylan Şen, Gülbahar Ustaoğlu, Erkan Özcan\",\"doi\":\"10.1186/s12903-025-06038-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The additional use of agents with antibacterial and anti-inflammatory activities, such as hyaluronic acid in treating periodontal disease, has recently become popular. This study aimed to evaluate the effects of using an interdental brush dipped in 0.2% HA gel on clinical periodontal parameters.Methods: This randomized controlled trial was conducted among 60 patients with stages II/III grades A/B periodontitis. After full-mouth scaling root planning and oral hygiene training, the patients were divided into two groups; the test group was asked to use an interdental brush dipped in 0.2% HA, while the control group was asked to use a regular interdental brush. Clinical periodontal parameters [ gingival index (GI), plaque index (PI), papillary bleeding index (PBI), pocket depth (PD), and clinical attachment loss (CAL) ] were assessed at baseline and in the 1st and 3rd months after treatment.Results: Clinical periodontal parameters were improved in control and test groups at the 1 and 3-month compared to baseline (p < 0.05). The 1st- and 3rd-month PBIs were significantly lower in the test group (p < 0.05). There was no significant difference between the test and control groups regarding PI, PD, GI, and CAL between the follow-up times.Conclusions: Although the clinical efficacy of the tested methods of interdental brush use was similar, it can be concluded that the use of an interdental brush dipped in HA may contribute to the reduction of gingival bleeding in the early period.Clinical significance: Incorporating HA into the oral hygiene regime after periodontitis treatment using an interdental brush is a useful and practical method. NAME OF THE REGISTRY: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT06309797.Date of registration: 07/03/2024 \\\"Retrospectively registered\\\". URL: https://clinicaltrials.gov/study/NCT06309797.\",\"PeriodicalId\":9072,\"journal\":{\"name\":\"BMC Oral Health\",\"volume\":\"25 1\",\"pages\":\"635\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023370/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Oral Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12903-025-06038-7\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Oral Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12903-025-06038-7","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

背景：近年来，具有抗菌和抗炎活性的药物的额外使用，如透明质酸在治疗牙周病方面越来越受欢迎。本研究旨在评估使用含0.2% HA凝胶的牙间刷对临床牙周参数的影响。方法：本随机对照试验在60例II/III期A/B级牙周炎患者中进行。患者在完成全口洗牙、牙根规划和口腔卫生培训后分为两组；试验组使用含0.2% HA的牙间刷，对照组使用普通牙间刷。临床牙周参数[牙龈指数（GI）、菌斑指数（PI）、乳头状出血指数（PBI）、牙袋深度（PD）和临床附着丧失（CAL）]在基线和治疗后1个月和3个月进行评估。结果：对照组和试验组在1个月和3个月时的临床牙周参数均较基线有所改善(p)。结论：虽然两种牙间刷使用方法的临床疗效相似，但可以得出结论，使用浸有透明质酸的牙间刷可能有助于减少早期牙龈出血。临床意义：使用牙间刷治疗牙周炎后，将透明质酸纳入口腔卫生制度是一种有用和实用的方法。注册中心名称：https://clinicaltrials.gov/试验注册编号：NCT06309797。注册日期：07/03/2024“追溯注册”。URL: https://clinicaltrials.gov/study/NCT06309797。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Evaluation of the effects of using an interdental brush dipped in 0.2% hyaluronic acid gel on clinical periodontal parameters among patients with periodontitis: a randomized controlled trial.

Background: The additional use of agents with antibacterial and anti-inflammatory activities, such as hyaluronic acid in treating periodontal disease, has recently become popular. This study aimed to evaluate the effects of using an interdental brush dipped in 0.2% HA gel on clinical periodontal parameters.

Methods: This randomized controlled trial was conducted among 60 patients with stages II/III grades A/B periodontitis. After full-mouth scaling root planning and oral hygiene training, the patients were divided into two groups; the test group was asked to use an interdental brush dipped in 0.2% HA, while the control group was asked to use a regular interdental brush. Clinical periodontal parameters [ gingival index (GI), plaque index (PI), papillary bleeding index (PBI), pocket depth (PD), and clinical attachment loss (CAL) ] were assessed at baseline and in the 1st and 3rd months after treatment.

Results: Clinical periodontal parameters were improved in control and test groups at the 1 and 3-month compared to baseline (p < 0.05). The 1st- and 3rd-month PBIs were significantly lower in the test group (p < 0.05). There was no significant difference between the test and control groups regarding PI, PD, GI, and CAL between the follow-up times.

Conclusions: Although the clinical efficacy of the tested methods of interdental brush use was similar, it can be concluded that the use of an interdental brush dipped in HA may contribute to the reduction of gingival bleeding in the early period.

Clinical significance: Incorporating HA into the oral hygiene regime after periodontitis treatment using an interdental brush is a useful and practical method. NAME OF THE REGISTRY: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT06309797.

Date of registration: 07/03/2024 "Retrospectively registered". URL: https://clinicaltrials.gov/study/NCT06309797.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

BMC Oral Health DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

6.90%

发文量

481

审稿时长

6-12 weeks

期刊介绍： BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.