编者注：AMPK通过激活CAMKK2导致lkb1缺陷细胞的细胞周期阻滞。

IF 4.1 2区医学 Q2 CELL BIOLOGY

Molecular Cancer Research Pub Date : 2025-05-02 DOI:10.1158/1541-7786.MCR-25-0265

Sarah Fogarty, Fiona A Ross, Diana Vara Ciruelos, Alexander Gray, Graeme J Gowans, D Grahame Hardie

引用次数: 0

摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Editor's Note: AMPK Causes Cell Cycle Arrest in LKB1-Deficient Cells via Activation of CAMKK2.

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来源期刊

Molecular Cancer Research 医学-细胞生物学

CiteScore

9.90

自引率

0.00%

发文量

280

审稿时长

4-8 weeks

期刊介绍： Molecular Cancer Research publishes articles describing novel basic cancer research discoveries of broad interest to the field. Studies must be of demonstrated significance, and the journal prioritizes analyses performed at the molecular and cellular level that reveal novel mechanistic insight into pathways and processes linked to cancer risk, development, and/or progression. Areas of emphasis include all cancer-associated pathways (including cell-cycle regulation; cell death; chromatin regulation; DNA damage and repair; gene and RNA regulation; genomics; oncogenes and tumor suppressors; signal transduction; and tumor microenvironment), in addition to studies describing new molecular mechanisms and interactions that support cancer phenotypes. For full consideration, primary research submissions must provide significant novel insight into existing pathway functions or address new hypotheses associated with cancer-relevant biologic questions.