模拟高级别胶质瘤的微囊性脑膜瘤氟昔洛碱- pet摄取1例报告。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-10-01 Epub Date: 2025-04-24 DOI:10.1097/RLU.0000000000005924

Junki Takenaka, Kenji Hirata, Shiro Watanabe, Yukitomo Ishi, Kohsuke Kudo

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引用次数: 0

摘要

一名69岁无症状女性接受磁共振成像（MRI）检查，发现左侧顶叶肿瘤疑似高级别胶质瘤（HGG）。[18F]氟氯烟素-正电子发射断层扫描（PET）反映氨基酸代谢，显示中度摄取[SUVmax 1.4，肿瘤与正常比（TNR） 1.9]，与HGG一致，而[18F]氟脱氧葡萄糖-PET显示低摄取（SUVmax 2.5, TNR 0.22），这是HGG的不典型。手术和病理检查证实了微囊性脑膜瘤的诊断，这是一种罕见的1级亚型。由于l-氨基酸转运蛋白的表达，微囊性脑膜瘤在磁共振成像和[18F]氟氯洛夫- pet上与HGG相似，使诊断复杂化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fluciclovine-PET Uptake in Microcystic Meningioma Mimicking High-grade Glioma: A Case Report.

A 69-year-old asymptomatic woman underwent magnetic resonance imaging (MRI), revealing a left parietal lobe tumor suspected to be a high-grade glioma (HGG). [ 18 F]Fluciclovine-positron emission tomography (PET), which reflects amino acid metabolism, showed moderate uptake [SUVmax 1.4, tumor-to-normal ratio (TNR) 1.9], consistent with HGG, whereas [ 18 F]fluorodeoxyglucose-PET findings demonstrated low uptake (SUVmax 2.5, TNR 0.22), which is atypical for HGG. Surgical and pathologic investigations confirmed the diagnosis of microcystic meningioma, a rare subtype classified as grade 1. Microcystic meningiomas mimic HGG on magnetic resonance imaging and [ 18 F]fluciclovine-PET due to l -amino acid transporter expression, complicating diagnosis.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.