钯催化烷基双硼酯的交叉偶联。

IF 2.5 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ChemistryOpen Pub Date : 2025-04-10 DOI:10.1002/open.202500195

Philip P Scott, Christopher E Baird, Elizabeth A Kraichely, Liam M Radeke, Timothy J Barker

{"title":"钯催化烷基双硼酯的交叉偶联。","authors":"Philip P Scott, Christopher E Baird, Elizabeth A Kraichely, Liam M Radeke, Timothy J Barker","doi":"10.1002/open.202500195","DOIUrl":null,"url":null,"abstract":"A Pd-catalyzed cross-coupling between alkylbisboronic esters and aryl bromides is described. A variety of aryl bromides are found to be competent substrates in the reaction. Different alkyl chain lengths of the alkylbisboronic esters are examined, and a two-carbon linker is found to be of the optimal chain length. Several competition experiments are performed to better understand the mechanism of the reaction.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e2500195"},"PeriodicalIF":2.5000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pd-Catalyzed Cross-Coupling of Alkylbisboronic Esters.\",\"authors\":\"Philip P Scott, Christopher E Baird, Elizabeth A Kraichely, Liam M Radeke, Timothy J Barker\",\"doi\":\"10.1002/open.202500195\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A Pd-catalyzed cross-coupling between alkylbisboronic esters and aryl bromides is described. A variety of aryl bromides are found to be competent substrates in the reaction. Different alkyl chain lengths of the alkylbisboronic esters are examined, and a two-carbon linker is found to be of the optimal chain length. Several competition experiments are performed to better understand the mechanism of the reaction.\",\"PeriodicalId\":9831,\"journal\":{\"name\":\"ChemistryOpen\",\"volume\":\" \",\"pages\":\"e2500195\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-04-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ChemistryOpen\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1002/open.202500195\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemistryOpen","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/open.202500195","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

描述了一种pd催化的烷基二硼酯与芳基溴间的交叉偶联反应。发现各种芳基溴在反应中是合适的底物。考察了烷基二硼酯的不同链长，确定了最佳链长为二碳的连接剂。为了更好地了解反应的机理，进行了几个竞争实验。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Pd-Catalyzed Cross-Coupling of Alkylbisboronic Esters.

A Pd-catalyzed cross-coupling between alkylbisboronic esters and aryl bromides is described. A variety of aryl bromides are found to be competent substrates in the reaction. Different alkyl chain lengths of the alkylbisboronic esters are examined, and a two-carbon linker is found to be of the optimal chain length. Several competition experiments are performed to better understand the mechanism of the reaction.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

ChemistryOpen CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

4.80

自引率

4.30%

发文量

143

审稿时长

1 months

期刊介绍： ChemistryOpen is a multidisciplinary, gold-road open-access, international forum for the publication of outstanding Reviews, Full Papers, and Communications from all areas of chemistry and related fields. It is co-owned by 16 continental European Chemical Societies, who have banded together in the alliance called ChemPubSoc Europe for the purpose of publishing high-quality journals in the field of chemistry and its border disciplines. As some of the governments of the countries represented in ChemPubSoc Europe have strongly recommended that the research conducted with their funding is freely accessible for all readers (Open Access), ChemPubSoc Europe was concerned that no journal for which the ethical standards were monitored by a chemical society was available for such papers. ChemistryOpen fills this gap.