非心脏手术治疗严重肺动脉高压:1例患者2例手术及文献回顾。

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL
Annals of Medicine and Surgery Pub Date : 2025-04-16 eCollection Date: 2025-05-01 DOI:10.1097/MS9.0000000000002828
Maciej Wiewiora, Alicja Nowowiejska-Wiewiora, Mariusz Gasior, Jerzy Piecuch
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引用次数: 0

摘要

简介和重要性:我们分析了在胆道梗阻过程中因复发性黄疸而接受手术治疗的严重肺动脉高压(PAH)患者和乳腺癌术后3年的多模式治疗方法。病例介绍:一名66岁女性,有5年与硬皮病相关的多环芳烃病史。由于胆管炎,她接受了胆总管内窥镜支架置入术。在手术期间,由于胆道梗阻期间反复出现黄疸,她接受了三轮内镜下从胆总管取出假体和重新置入手术。她接受了硬膜外胸廓麻醉和静脉镇静的手术。三年后,病人被诊断出患有乳腺癌。她接受了局部神经轴阻滞和静脉镇静手术,并进行了乳房切除术和腋窝淋巴结切除术。临床讨论:根据《肺高压诊断与治疗指南》,在手术前不能给出一般性建议。肺动脉高压(PH)治疗的围手术期优化应包括功能状态、疾病严重程度和合并症的评估。心脏病专家在患者计划手术前对PH的最佳特异性治疗和最佳手术时间的选择至关重要。第二个非常重要的因素是麻醉类型的选择。结论:本例患者手术风险高,一是腹部手术面积大,二是术前未进行特殊修饰治疗。第三,PH严重程度非常严重,肺动脉压高于全身血压。如本例所述,如果采用当前的手术和麻醉策略,晚期PH患者在非心脏手术中可以经历相对平稳的术中过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Noncardiac surgery for severe pulmonary hypertension: two surgeries in one patient and a review of the literature.

Introduction and importance: We present an analysis of the use of the multimodality approach for the treatment of patients with severe pulmonary arterial hypertension (PAH) who underwent surgery due to recurrent jaundice in the course of biliary obstruction and three years after surgery for breast cancer.

Case presentation: A 66-year-old woman with a 5-year documented history of associated PAH related to scleroderomia. Because of cholangitis, she underwent endoscopic stenting of the common bile duct. At the time of the operation, she underwent three rounds of endoscopic removal of the prosthesis from the choledochal duct and restenting procedures due to recurrent jaundice during biliary obstruction. She underwent surgery via epidural thoracic anesthesia with intravenous sedation. Three years later, the patient was diagnosed with breast cancer. She underwent surgery via regional neuraxial blocks with intravenous sedation, and mastectomy with axillary lymphadenectomy was performed.

Clinical discussion: According to the Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension, a general recommendation before surgery cannot be made. The perioperative optimization of pulmonary hypertension (PH) therapy should include assessments of functional status, severity of disease and comorbidities. The optimal specific treatment of PH by a cardiologist before the planned surgery of a patient and the selection of the optimal surgery time were crucial. The second very important element was the selection of the type of anesthesia.

Conclusion: Our patient underwent high-risk surgery because, first, a large abdominal procedure was performed, and second, the operation was performed without the possibility of special preoperative modification therapy. The third, PH severity was very advanced, with higher pulmonary artery pressure than systemic blood pressure. Patients with advanced PH could experience a relatively smooth intra-operative course in non-cardiac surgery when managed with current operative and anesthetic strategies, as in the case described.

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Annals of Medicine and Surgery
Annals of Medicine and Surgery MEDICINE, GENERAL & INTERNAL-
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