Kwabena Agbedinu, Sylvester Antwi, Livingstone Aduse-Poku, Patrick Kafui Akakpo, Harriet Larrious-Lartey, Valerie Ofori Aboah, Samuel Mensah, Veneranda Nyarko, Forster Amponsah-Manu, Josephine Nsaful, Rose Dampson, Michael Nortey, Ijeoma Aja, Mohammed Sheriff, Moses Abdulai Dokurugu, Nelson Affram, Alex Mremi, Theresia Mwakyembe, Moses Kamita, Linda Kaljee, Evelyn Jiagge
{"title":"低收入和中等收入国家癌症诊断和治疗障碍的范围审查。","authors":"Kwabena Agbedinu, Sylvester Antwi, Livingstone Aduse-Poku, Patrick Kafui Akakpo, Harriet Larrious-Lartey, Valerie Ofori Aboah, Samuel Mensah, Veneranda Nyarko, Forster Amponsah-Manu, Josephine Nsaful, Rose Dampson, Michael Nortey, Ijeoma Aja, Mohammed Sheriff, Moses Abdulai Dokurugu, Nelson Affram, Alex Mremi, Theresia Mwakyembe, Moses Kamita, Linda Kaljee, Evelyn Jiagge","doi":"10.1158/1055-9965.EPI-25-0120","DOIUrl":null,"url":null,"abstract":"<p><p>Cancer remains a significant global health challenge, with low- and middle-income countries (LMICs) disproportionately burdened by high mortality rates despite a lower overall incidence. Barriers to timely diagnosis and care exacerbate these disparities. This scoping review synthesize existing literature on barriers for women in LMICs following the Joanna Briggs Institute methodology and PRISMA-ScR guidelines. Studies on women in LMICs reporting barriers to accessing care for breast, colorectal, lung, cervix uteri, thyroid, corpus uteri, and stomach cancers were included. 29 studies involving 7,031 participants were included. The most common barriers included financial challenges (65.5%), geographical obstacles (34.5%), health system limitations (55.2%), and low health literacy (51.7%). Patients experienced significant delays, averaging 7.4 months from symptom onset to diagnosis and 4.9 months from diagnosis to treatment initiation. Structural issues such as limited diagnostic services, inadequate healthcare infrastructure, and healthcare provider shortages were widespread. Addressing the multifaceted barriers to cancer care in LMICs requires comprehensive strategies, including increasing financial support, decentralizing care services, improving healthcare infrastructure, and enhancing education for patients and providers. Policymakers and stakeholders should prioritize investments in cancer care to reduce disparities and improve outcomes. These findings will inform strategies for improving cancer care in low-resource settings globally.</p>","PeriodicalId":9458,"journal":{"name":"Cancer Epidemiology Biomarkers & Prevention","volume":" ","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Scoping Review on Barriers to Cancer Diagnosis and Care in Low- and Middle-Income Countries.\",\"authors\":\"Kwabena Agbedinu, Sylvester Antwi, Livingstone Aduse-Poku, Patrick Kafui Akakpo, Harriet Larrious-Lartey, Valerie Ofori Aboah, Samuel Mensah, Veneranda Nyarko, Forster Amponsah-Manu, Josephine Nsaful, Rose Dampson, Michael Nortey, Ijeoma Aja, Mohammed Sheriff, Moses Abdulai Dokurugu, Nelson Affram, Alex Mremi, Theresia Mwakyembe, Moses Kamita, Linda Kaljee, Evelyn Jiagge\",\"doi\":\"10.1158/1055-9965.EPI-25-0120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Cancer remains a significant global health challenge, with low- and middle-income countries (LMICs) disproportionately burdened by high mortality rates despite a lower overall incidence. 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A Scoping Review on Barriers to Cancer Diagnosis and Care in Low- and Middle-Income Countries.
Cancer remains a significant global health challenge, with low- and middle-income countries (LMICs) disproportionately burdened by high mortality rates despite a lower overall incidence. Barriers to timely diagnosis and care exacerbate these disparities. This scoping review synthesize existing literature on barriers for women in LMICs following the Joanna Briggs Institute methodology and PRISMA-ScR guidelines. Studies on women in LMICs reporting barriers to accessing care for breast, colorectal, lung, cervix uteri, thyroid, corpus uteri, and stomach cancers were included. 29 studies involving 7,031 participants were included. The most common barriers included financial challenges (65.5%), geographical obstacles (34.5%), health system limitations (55.2%), and low health literacy (51.7%). Patients experienced significant delays, averaging 7.4 months from symptom onset to diagnosis and 4.9 months from diagnosis to treatment initiation. Structural issues such as limited diagnostic services, inadequate healthcare infrastructure, and healthcare provider shortages were widespread. Addressing the multifaceted barriers to cancer care in LMICs requires comprehensive strategies, including increasing financial support, decentralizing care services, improving healthcare infrastructure, and enhancing education for patients and providers. Policymakers and stakeholders should prioritize investments in cancer care to reduce disparities and improve outcomes. These findings will inform strategies for improving cancer care in low-resource settings globally.
期刊介绍:
Cancer Epidemiology, Biomarkers & Prevention publishes original peer-reviewed, population-based research on cancer etiology, prevention, surveillance, and survivorship. The following topics are of special interest: descriptive, analytical, and molecular epidemiology; biomarkers including assay development, validation, and application; chemoprevention and other types of prevention research in the context of descriptive and observational studies; the role of behavioral factors in cancer etiology and prevention; survivorship studies; risk factors; implementation science and cancer care delivery; and the science of cancer health disparities. Besides welcoming manuscripts that address individual subjects in any of the relevant disciplines, CEBP editors encourage the submission of manuscripts with a transdisciplinary approach.