中国6-16岁在校学生注意缺陷多动障碍患病率及合并症调查

IF 3.6 3区 医学 Q1 PSYCHIATRY
Jingran Liu, Zhongliang Jiang, Fenghua Li, Yi Zheng, Yonghua Cui, Hui Xu, Ying Li
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引用次数: 0

摘要

背景:注意缺陷多动障碍(ADHD)是一种常见的神经发育障碍。尽管具有重要意义,但中国尚未开展大规模流行病学研究,评估儿童和青少年ADHD及其相关合并症。方法:在中国对73992名6至16岁的儿童和青少年进行的全国流行病学调查中,我们使用CBCL、MINI-KID和DSM-IV来识别ADHD及其合并症。卡方检验用于比较不同年龄和性别群体的患病率估计值。结果:总体ADHD患病率估计为6.4% (95% CI: 6.2-7.0%)。按亚型划分,ADHD-I患病率为3.9%,ADHD-C患病率为1.7%,ADHD-H患病率为0.9%。结论:ADHD是一种常见的神经发育障碍,具有较高的合并症发生率,在不同的亚型、年龄和性别之间差异很大。这些临床异质性使管理复杂化,并强调需要量身定制的干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and comorbidity of attention deficit hyperactivity disorder in Chinese school-attending students aged 6-16: a national survey.

Background: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder. Despite its significance, no large-scale epidemiological study assessing ADHD, and its associated comorbidities in children and adolescents has been conducted in China.

Methods: Within a national epidemiological survey of 73,992 children and adolescents aged between 6 and 16 in China, we used the CBCL, MINI-KID, and DSM-IV to identify ADHD and its comorbid conditions. Chi-square tests were utilized to compare the prevalence estimates across varied age and sex groups.

Results: The overall ADHD prevalence was estimated at 6.4% (95% CI: 6.2-7.0%). Broken down by subtypes, ADHD-I had a prevalence of 3.9%, ADHD-C was at 1.7%, and ADHD-H was at 0.9%. Boys and the younger age bracket recorded higher prevalence rates for ADHD and its subtypes (p < 0.001). Among ADHD-diagnosed individuals, 53% exhibited at least one comorbid psychiatric disorder. Oppositional defiant disorder/conduct disorder (ODD/CD) was the most prevalent comorbidity for ADHD-C and ADHD-H, at 58%, while anxiety disorders, at 17%, were predominant among ADHD-I cases. ODD/CD was notably higher among younger subjects (p < 0.001). In contrast, anxiety disorders were more frequent in older children and in girls (p < 0.001). Tic disorders showed a higher prevalence in younger boys, whereas mood and substance use disorders were more common in older boys (p < 0.001).

Conclusions: ADHD is a common neurodevelopmental disorder with high comorbidity rates that vary substantially across subtypes, age, and sex. These clinical heterogeneities complicate management and highlight the need for tailored interventions.

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来源期刊
CiteScore
6.60
自引率
2.70%
发文量
43
审稿时长
>12 weeks
期刊介绍: Annals of General Psychiatry considers manuscripts on all aspects of psychiatry, including neuroscience and psychological medicine. Both basic and clinical neuroscience contributions are encouraged. Annals of General Psychiatry emphasizes a biopsychosocial approach to illness and health and strongly supports and follows the principles of evidence-based medicine. As an open access journal, Annals of General Psychiatry facilitates the worldwide distribution of high quality psychiatry and mental health research. The journal considers submissions on a wide range of topics including, but not limited to, psychopharmacology, forensic psychiatry, psychotic disorders, psychiatric genetics, and mood and anxiety disorders.
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