子宫内膜异位症的研究进展：研究生殖障碍的动物模型。

IF 3.1 2区生物学 Q2 REPRODUCTIVE BIOLOGY

Biology of Reproduction Pub Date : 2025-04-14 DOI:10.1093/biolre/ioaf089

Mingjuan Zhou, Xingchen Zhou, Xipeng Wang

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引用次数: 0

摘要

子宫内膜异位症（EMS）是女性不孕症的重要因素，其潜在机制尚不清楚。动物模型是研究疾病进展和评估治疗方案的重要工具。本文综述了利用动物模型（包括非人灵长类动物和啮齿动物）建立ems相关不孕模型的研究进展。本研究全面综述了在动物模型中对子宫内膜异位症相关不孕症机制的最新研究进展。它为研究人员选择合适的动物模型来研究这种疾病的发病机制和药物治疗提供了宝贵的资源。

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Advances in endometriosis research: animal models for the study of reproductive disorders.

Endometriosis (EMS) is a significant contributor to female infertility, with its underlying mechanisms remaining inadequately understood. Animal models serve as essential tools for investigating disease progression and evaluating treatment options. This article reviews the advancements in research involving animal models, including non-human primates and rodents, in the development of EMS-related infertility models. This study provides a comprehensive overview of the latest advancements in understanding the mechanisms of infertility related to endometriosis in animal models. It serves as a valuable resource for researchers seeking guidance in choosing suitable animal models for investigations on the pathogenesis and pharmacological treatment of this condition.

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来源期刊

Biology of Reproduction 生物-生殖生物学

CiteScore

6.30

自引率

5.60%

发文量

214

审稿时长

1 months

期刊介绍： Biology of Reproduction (BOR) is the official journal of the Society for the Study of Reproduction and publishes original research on a broad range of topics in the field of reproductive biology, as well as reviews on topics of current importance or controversy. BOR is consistently one of the most highly cited journals publishing original research in the field of reproductive biology.